Della Enterprises, Inc. will develop a programmable laboratory incubator or PLIN which is capable of autonomously carrying out complex in-vitro cell culture studies. This incubator design supports the following innovations: 1) vastly increased capabilities for tissue plate storage due to a compact method of storage and retrieval, 2) automated access to multiple stock solutions and dosing sources, 3) the ability to add or dispose of fluids to/from cellular cultures, 4) the ability to add or remove new supplies like tiuuse culture plates and pipettes without interrupting ongoing experiments, 5) automated monitoring of cellular status and integration of this information into the protocol, 6) the ability to run complete experiments, or large portions of them in a completely enclosed and aseptic environment, 7) an intuitive graphical user interface that allows simple construction of complete assays and 8) 3D simulation of all operations to confirm proper programming of experimental procedures.
