Not to be confused with the other SBIR firm Integrated Sensors Inc, Integrated Sensors, *LLC* - aka I-S - focused early on the commercialization of a new class of transformational radiation sensors. Now relocated to Florida - from Toledo - the firm is among the first world-wide to apply the high gain, high-performance properties of low cost PDP-TV (plasma display panel) technology to radiation detection. This has supported development of the Plasma Panel Sensor (PPS).Plasma Panel Photosensor (PPPS)* and Plasma Panel Scintillation Detector (PPSD)* -- hybrid gaseous/solid state detection devices with the potential to replace conventional vacuum, gaseous, and solid state detectors, providing next-generation imaging performance and significant cost savings for a number of critical applications in medical imaging, homeland security and high-energy nuclear physics. I-S has also initiated a research program on ultra-fast transmissive (UFT) particle and photon beam monitors. UFT-devices can monitor any type of ionizing beam for external beam radiation therapy (EBRT) and can operate either upstream (in vacuum) or downstream (in air) from the exit nozzle or multileaf collimator with exceptional performance capability. Results show order-of-magnitude advantages over ionization chambers for position resolution, readout time and beam hardening. UFT-beam monitors are also being developed for precision position (? 0.1 mm) and time-of-flight (? 100 ps) measurements in heavy-ion and rare isotope or exotic particle beam accelerators from B-10 (+5 charge) to U-238 (+62 charge) nuclei.