Company Profile

Zalgen Labs LLC
Profile last edited on: 11/15/2018      CAGE: 6LNY3      UEI: LVBZDR1MSAQ3

Business Identifier: Immunotherapeutics, novel vaccines, and reliable, rapid, and affordable diagnostic platforms
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Location Information

20271 Goldenrod Lane Suite 2083
Germantown, MD 20876
   (504) 444-7047
Location: Single
Congr. District: 06
County: Montgomery

Public Profile

Zalgen has core competency in the development of platforms for generation of high quality recombinant proteins from difficult-to-express genes. The firm's approaches are supported by the development of first-to-field-use rapid diagnostic tests for Lassa hemorrhagic fever (LHF) by a consortium of academic, institutional, and biotechnology entities, led by one of Zalgens' founders, These diagnostics are changing the understanding of epidemiological, immunological, and basic research notions in LHF, contributing toimprovements in the management and successful outcome of this viral disease. Principals of the firm have developed effective methods for production of Lassa virus-like particles (VLP), which are empty and non-infectious virions containing all the immunologically relevant viral proteins in quasi-native conformation. Lassa VLP are being tested as possible next generation vaccine platforms for LHF, and have shown efficacy in preliminary in vivo studies. This VLP technology has broad applications in vaccine and diagnostic platform development for a wide array of enveloped viruses. These two programs are factors in the development of first-in-class immunotherapeutics for prophylaxis and treatment of LHF. he first three fully human monoclonal antibodies, administered in single or cocktail formats have demonstrated remarkable efficacy in relevant animal models in Biosafety Level-4 (BSL-4) settings. Zalgen

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Synopsis: Awardee Business Condition

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Key People / Management

  Luis Manuel Branco -- President & Co-Founder

  Matthew L Boisen

  Robert F Garry -- Co-Founder

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