POINT Biomedical Corporation is a development stage company focusing on novel technologies for the delivery of diagnostic and therapeutic compounds. POINT Biomedical has developed acoustically responsive microspheres using proprietary biomaterial technologies to address two large market opportunities, primarily in the area of cardiology: ultrasound contrast agents and ultrasound targeted drug delivery. biSphere Configuration: Shell within a Shell POINT Biomedical has developed a proprietary hollow microsphere technology platform that is based on a biSphere configuration: a shell within a shell. The inner shell, formed from biodegradable polymers, provides physical structure and controls acoustic response; while the outer layer functions as the biological interface and can provide a scaffold for site-specific targeting ligands. Each layer or shell can be independently modified to fulfill specific application requirements. The core or payload space can be filled with a gas, such as nitrogen, for ultrasound imaging as in our myocardial perfusion agent, CARDIOsphere, or with biotherapeutic agents for drug delivery applications.
