Luciole is a start-up company focusing on the discovery and development of small molecules that accelerate the repair of oxidative damage to mitochondrial DNA (mtDNA). The company has combined decades of expertise in mitochondrial function, drug discovery and development, and use of the virtual company model to become the leader in correcting oxidative damage to mtDNA. Luciole is applying cutting edge science to enhance the functionality of OGG1 (8-oxoguanine DNA glycosylase), the key enzyme in the initiation of base excision repair (BER) of mtDNA.
