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Galera Therapeutics LLC

Galera Therapeutics LLC

Profile last edited on: 2/19/2021
2 West Liberty Boulevard Suite 110
Malvern, PA 19355
  (610) 725-1511
Business Identifier: Therapeutic agents for preventing damage to normal tissues during radiationcancer treatment
Public Profile:
Galera Therapeutics is a privately held, clinical-stage biotechnology company organIzed around discovery and developiment of novel therapeutics having the potential to transform how radiation therapy is used in the treatment of cancer patients. A particular focus of the firm is the reduction of Oral mucositis - a condition that occurs during cancer treatment as excessive superoxide is generated and breaks down epithelial cells that line the mouth. Targeting oxygen metabolic pathways, Galeras lead product candidate is GC4419, a highly selective and potent small molecule superoxide dismutase enzyme mimetic that rapidly converts superoxide to hydrogen peroxide and oxygen. GC4419 achieved positive results in a Phase 2b clinical trial, which demonstrated its ability to reduce the incidence and duration of radiation-induced severe oral mucositis in patients with head and neck cancer, its lead indication. The U.S. Food and Drug Administration granted Fast Track and Breakthrough Therapy designations to GC4419.

 Synopsis: Awardee Business Condition
Year Founded First SBIR Year Date of Last Award
Employee Range VC funded? IP Holdings
Revenue Range Private/Public Exchange/Symbol :
 Most Recent SBIR Projects
Year Phase Agency Dollars Project Title
GC4419, an SOD Mimetic, as a Radiomodulator in Lung Cancer Patients Treated with SBRT

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Contact information

Innovation Development Institute, LLC

   45 Beach Bluff Avenue, Suite 300
     Swampscott,  MA 01907-1542

  Tel:  (781) 595-2920