Company Profile

Enbiotix Inc
Profile last edited on: 1/21/2022      CAGE: 70CA2      UEI: DMFLG44ZFLL9

Business Identifier: Transforming /revitalizing existing antibiotic classes to combat rise in drug-resistant bacterial infections
Year Founded
First Award
Latest Award
Program Status
Inactive (Acquired)
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Location Information

197 West Springfield Street
Boston, MA 02118
   (508) 400-1856
Location: Single
Congr. District: 07
County: Suffolk

Public Profile

In December 2021 it was announced that Swiss firm Polyphor - structured around discovery and development of macrocycle drugs addressing high unmet medical needs - had merged with EnBiotix with the new entity renamed Spexis. With limited SBIR involvement, Boston-based Enbiotix since 2013 had functioned as an engineered antibiotics company deploying novel systems and synthetic biology technologies developed by Prof. James J. Collins, the Termeer Professor of Medical Engineering & Science Professor, Department of Biological Engineering, MIT. These technologies enable the development of both novel antibiotics and potentiators of existing antibiotics having the potential to transform their spectrum of activity and resistance profile. With drug-resistant and drug-tolerant infections rapidly becoming a global health crisis, EnBiotixÂ’s robust product pipeline had addressed a wide range of acute and chronic infections to significantly impact the lives of patients.

Extent of SBIR involvement

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Synopsis: Awardee Business Condition

Employee Range
Revenue Range
VC funded?
Privately Held
Stock Info
IP Holdings

Awards Distribution by Agency

Key People / Management

  Jeffrey D Wager -- Chairman & CEO

  James J Collins -- Scientific Founder

  Michael Garrett -- Chief Business Officer

  Diane Joseph-Mccarthy -- Vice President, Translational Science

  Benjamin Perrone -- Business Development Manager

  Jeffrey A Radding -- Vice President Biology