Company Profile

DNAtrix Inc
Profile last edited on: 9/23/2020      CAGE: 5JY93      UEI: N5SVUABKNRB8

Business Identifier: Targeted oncolytic virus therapies for treating malignant glioma
Year Founded
2005
First Award
2014
Latest Award
2022
Program Status
Active
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Location Information

2450 Holcombe Boulevard Suite X+ 200
Houston, TX 77021
   (832) 930-2401
   info@dnatrix.com
   www.dnatrix.com
Location: Single
Congr. District: 18
County: Harris

Public Profile

DNAtrix is a privately held, clinical stage, biotechnology company developing virus-driven immunotherapies for cancer. An Alumni of the JLabs SanDiego. and having very limited SBIR Involvement, in 2012 DNAtrix had merged/acquired another SBIR firm, Vectorlogics of Birmingham, AL. Viruses are understood to be good at killing cells. Hence scientists have harnessed this ability by modifying a common cold virus so that it targets and kills cancer cells selectively. The Company’s lead product, DNX-2401, had been the culmination of more than a decade of scientific and clinical research and proved to be the most potent and effective oncolytic virus delivered to human brain tumors to that point. DNAtrix's oncolytic viruses initiate a chain reaction of tumor cell killing by selectively replicating within cancer cells (but not normal cells), triggering an immune response directed against tumors. DNAtrix has multiple virus candidates in clinical trials for cancers with urgent need for novel approaches. DNAtrixs oncolytic viruses initiate a chain reaction of tumor cell killing by selectively replicating within cancer cells (but not normal cells), triggering an immune response directed against tumors. DNAtrix has multiple virus candidates in clinical trials for cancers with urgent need for novel approaches.

Extent of SBIR involvement

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Synopsis: Awardee Business Condition

Employee Range
15-19
Revenue Range
1.5M-2M
VC funded?
Yes
Public/Private
Privately Held
Stock Info
----
IP Holdings
1-4

Awards Distribution by Agency

Most Recent SBIR Projects

Year Phase Agency Total Amount
2022 2 NIH $852,569
Project Title: Phase 1 Study of DNX-2440 for Resectable Colorectal Liver Metastasis - IND 018569
2014 1 NIH $160,632
Project Title: Ex Vivo Purging Strategy for Treatment of Multiple Myeloma

Key People / Management

  Frank Tufaro -- Former Chief Executive Officer

  Charles Conrad -- Co-Founder

  Brett Ewald -- Vice President, Development

  Juan Fueyo -- Co-Founder

  Cande Manzano -- Co-Founder

  Grant Mcfadden -- Advisor

  Joan Marie Robbins

  Al Yung -- Founder