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Basking Biosciences

Basking Biosciences

Profile last edited on: 2/12/21
1275 Kinnear Road
Columbus, OH 43212
  (919) 423-5043
Business Identifier: Reversible thrombolytic therapy for acute ischemic stroke (AIS)
Public Profile:
With a focus on addressing commercialization of technologies initiated at - and licensed from - Duke and Ohio State Universities, the initial focus is on developing a therapy that would restore blood flow to the brain during ischemic stroke with the objective of preventing hemorrhage and long-term damage - effectively everaging aptamer technology to improve outcomes in ischemic stroke. The second leading cause of death globally and a leading cause of serious long-term disability, stroke is largely under-treated with only a small percentage of patients provided active intervention rapidly and safely to restore blood flow to the brain and limit neurological damage. Basking Biosciences' lead compound leverages the proven aptamer technology platform developed at Duke to create a highly specific inhibitor of Von Willebrand Factor (VWF) and a paired reversal agent. This paired therapy enables rapid reversibility of DTRI-031s effect and mitigates the bleeding risk that has limited the adoption of tPA as a thrombolytic in ischemic stroke and derailed many other development programs. VWFs central role in both clot formation, stabilization and remodeling make it a very attractive target for anti-thrombotic intervention.

 Synopsis: Awardee Business Condition
Year Founded First SBIR Year Date of Last Award
Employee Range VC funded? IP Holdings
Revenue Range Private/Public Exchange/Symbol :
 Most Recent SBIR Projects
Year Phase Agency Dollars Project Title
A Reversible Aptamer Based Therapeutic to Treat Stroke

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Contact information

Innovation Development Institute, LLC

   45 Beach Bluff Avenue, Suite 300
     Swampscott,  MA 01907-1542

  Tel:  (781) 595-2920