Company Profile

Asymmetrex LLC
Profile last edited on: 10/12/21      CAGE:       UEI: D3JTJM83KNT3

Business Identifier: Adult stem cell research
Year Founded
2013
First Award
2020
Latest Award
2020
Program Status
Active
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Location Information

39 Sheridan Street
Boston, MA 02130
   (617) 990-6819
   contact@asymmetrex.com
   www.asymmetrex.com
Location: Single
Congr. District: 08
County: Suffolk

Public Profile

Assymmetrex LLC is a life sciences biotechnology company structured around innovative usage of adult tissue stem cells - advancing the potential of adult tissue set cells for use in routine medical practice. Found in the bodies of children and adults, adult tissue stem cells are a small fraction of the cells (less than 1 per 1000) that make up organs and tissues like the liver, cornea, skin, muscles, hair, brain, and bone marrow. Despite their small fraction, they are responsible for continuously renewing and repairing the body. With the normal role of tissue cells being maintainenance and restoration of organs and tissues, when obtained from a donating person, tissue cells have an inherent ability to reconstitute severely damaged tissues due to injury or disease in the recipient person. Currently, however, this type of tissue stem cell transplantation treatments are only available for a very few applications, eg bone marrow and cornea of the eye. Stem cell transplantation therapies have the potential for use in various other tissues .. but actual usage is currently not possible. in major part tis is due to insufficient quantities of donor stem cells – often undermining the effectiveness of the tissue stem cell treatments that actually are available. Asymmetrex holds adult stem cell patents for technologies that promote the multiplication of adult tissue stem cells. Tested so far for tissue stem cells found in the liver, lung, pancreas, muscle, skin and hair follicle, the technologies have the potential to produce therapeutic human tissue stem cells by the pound, trillions of cells at a time. Unlike other presently popularized strategies based on pluripotent stem cells, Asymmetrex’s adult stem cell medicine technology produces normal cells without high rates of mutation or tumor-forming properties. In collaboration with strategic partners, Asymmetrex is developing robust manufacturing processes that are targeted at producing medically important tissue stem cells and their differentiated derivative cells for use in transplantation therapies and drug development. A. further, long-standing challenge in stem cell biomedicine is lack of means to identify and count tissue stem cells meaning that - even the available tissue stem cell therapies like bone marrow transplantation - cannot be reliably optimized to achieve better treatment outcomes. Employing its internationally recognized, special research expertise in unique adult tissue stem cell properties, Asymmetrex has developed several technologies that make it now possible either ti count tissue stem cells directly or to estimate their number precisely -- for the first time, offering the means to monitor tissue stem cell number and quality for applications in regenerative medicine and drug developmen

Extent of SBIR involvement

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Synopsis: Awardee Business Condition

Employee Range
1-4
Revenue Range
Less than .5M
VC funded?
No
Public/Private
Privately Held
Stock Info
----
IP Holdings
15-19

Awards Distribution by Agency

Most Recent SBIR Projects

Year Phase Agency Total Amount
2020 1 NIH $420,000
Project Title: Increased Validation of a First Method for Counting Tissue Stem Cells Specifically

Key People / Management

  James L Sherley -- President and CEO

Company News

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