AIKO Biotechnology, Inc. (âAIKOâ) is an early stage drug discovery company founded to characterize and validate therapeutic candidates for the management of pain, addiction and adverse side effects resulting from prescription pain reliever (opioid) use. AIKOâs lead drug candidates will significantly increase the safety and efficacy of opioids that are used by millions of pain sufferers and will offer safer, more effective treatments for opioid overdose and various addictions than any compounds currently available. The core technology is based on a new understanding of receptor pharmacology, documented in the research and patents of AIKO co-founders Drs. Wolfgang Sadée and Edward Bilsky. AIKOâs value lies in the expertise of its scientific team and their unique ability to conceptualize and evaluate drug candidates using a variety of sophisticated cellular assays and animal