Originally doing business as Advanced Circulatory Systems Inc, - after being renamed from being CPRx LLC, -- in December 2014 the firm was acquired by Zoll Medical Corporation with the firm to continue operations out of Minnesota as a part of Zolls Core Products division the firm. Zoll Medical had itself been acquired just previously - in 2012 - in a $2.2B transaction by Asahi Kasei Corporation. Interestingly, though by the earlier name of ResQSystems, the technology that underpins the firm had been spun out by Zoll, Closing the circle. Advanced Circulatory had been organized around using the bodys own mechanisms to enhance circulation without the use of pharmaceutical or other agents: a facemask with a regulator system to increase or decrease interior chest pressure during normal respiration or CPR to improve the hearts ability to enhance pre-load and cardiac output. The firm's Intrathoracic Pressure Regulation (IPR) therapy platform has far-reaching implications for multiple medical conditions. This non-invasive therapy can potentially protect the heart, brain and other vital organs when blood flow is compromised, giving rescuers, clinicians and caregivers the potential to return patients to a full life after critical medical emergencies.anufactures and markets advanced circulatory technology. The company primarily focuses on developing resuscitating technologies used to restore life and improve the quality of life for patients experiencing cardiac arrest, low blood pressure, and head injury. It offers a variety of defibrillators and monitors, automated external defibrillators (AED), ventilators, wearable defibrillators, intravascular temperature management technology, automated CPR technology, patient data management tools, fluid resuscitation technology, and intrathoracic pressure regulation (IPR) therapy. Shortly before the acqusition by Zoll