Present state unknown. Assumed out of business. Acclaim Biotechnology had developed products, therapeutics and strategies based on the receptor-mediated delivery technology. The Company used its platform technologies to develop therapeutics targeted to the liver and other tissues and organs. The lead product (CD-CS) is a patented fusion protein with a drug-metabolizing enzyme (CD) and a liver-targeting protein (CS) from the malarial parasite. The CS protein targets the surface receptors of the liver cells, while the CD enzyme converts a nontoxic prodrug to the toxic metabolite. This regimen is preferentially toxic to the proliferating tumor cells, and the non-tumor liver tissues and other organs are essentially not affected. Research conducted indicates that this approach is specific, efficiency and safe. Therefore, this product is particularly applicable for improving chemotherapy of liver cancer and liver metastasis, which affect tens of thousands of patients worldwide. Venture capitals and partners are welcome to join in developing and commercializing this novel technology
