Although the American elderberry species has not been cultivated, bred, or promoted as a medicinal plant like its European counterpart, university based variety trials indicate that the attributes of American elderberries complement, equal, or exceed the European cultivars currently in the market, suggesting a need for increased American elderberry production and product development. Purpose: To enhance international competitiveness of American agriculture by creating a domestic elderberry industry including manufacturing of elderberry-based nutraceuticals, herbal supplements and functional foods with superior attributes. To support increased economic opportunities and improve the quality of life in rural America by offering an easily grown alternative crop that is disease and pest resistant and commands a premium price in value-added products. To provide crop diversification to small and mid-sized farms seeking to retain and sustain farm communities by responding to a market driven by a growing consumer understanding of the link between diet and disease, aging baby boomer populations and soaring health care costs, coupled with advances in food science and nutrition. OBJECTIVES: I. Determine the feasibility of improving the marketability and profitability of American grown elderberries. II. Determine the varieties of elderberries most desirable for farmers to grow as specialty crops for nutraceuticals, herbal supplements and functional foods. APPROACH: I. Identify and rank attributes of selected S. nigra and S. canadensis cultivars that hold promise of being better performing varieties. Using published and unpublished data from European and American research, identify, evaluate and rank attributes of twelve elderberry cultivars within four data clusters. 1. Sensory evaluation: color, taste, smell, and viscosity 2. Horticultural attributes: habit, yield, vigor, disease and pest resistance, fruit load holding characteristics, and hardiness. 3. Bioactive components and profiles:'Total antioxidants, total phenolics, HPLC profiles, pH, Brix, moisture, and titratability acidity. 4. Total antioxidant capacity: ORAC II. Select cultivars for field analysis. Based on data from the multi-variant analysis outlined above, select eight varieties to carry forward to the applied research portion of the study. III. Harvest and process fruit. Harvest, process, and transport samples of the ripe fruit of eight varieties of field grown elderberries to university food science laboratories for evaluation. IV. Evaluate juices. Based on information gained from sensory evaluation, analysis of bioactive components and profiles, and determination of total antioxidant capacity, food scientists will accurately indicate and differentiate varietal elderberry juice qualities. V. Identify superior varieties. Identify varieties with the best qualities to become the platform for elderberry-based nutraceuticals, herbal supplements, and functional foods. VI. Disseminate information