SBIR-STTR Award

Biomedical Instrumentation for Extracorporeal Shock Wave Lithotripsy
Award last edited on: 11/22/02

Sponsored Program
SBIR
Awarding Agency
NSF
Total Award Amount
$275,000
Award Phase
2
Solicitation Topic Code
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Principal Investigator
Bruce Hartenbaum

Company Information

H-Tech Laboratories Inc

18152 Kingsport Drive
Malibu, CA 90265
   (310) 459-4610
   N/A
   N/A
Location: Single
Congr. District: 33
County: Los Angeles

Phase I

Contract Number: 8960493
Start Date: 00/00/00    Completed: 00/00/00
Phase I year
1989
Phase I Amount
$50,000
Extracorporeal shock wave lithotripsy (ESWL) has become the preferred method of removal for the majority of symptomatic renal, ureteral, and biliary calculi. Recently, medical research has revealed that ESWL can cause a variety of acute and possibly chronic injuries. The propagation and focusing of shock waves in, and their interaction with, tissue and calculi is sufficiently complex that the aspects of the pressure field contributing to injury and to stone fragmentation cannot yet be identified. The main objective of the research is to gain fundamental knowledge of the properties of convergent shock waves in tissues, and their interaction with stone materials. A concomitant objective is to employ the knowledge so gained to assess the feasibility of developing instrumentation to both diagnose and control the lithotripsy process. Polyvinylidene fluoride pressure transducers will be used to acquire shock pressure and scattered wave data. The data will be used in conjunction with numerical shock dynamics calculations to understand the propagation process and in developing an empirical scattering model. It is anticipated that it will be possible to predict key elements of the interaction process by the use of innovative algorithms and to use the algorithms as a basis for new lithotripter instrumentation.The potential commercial application as described by the awardee: A potential commercial application of the research is a new line of instrumentation that will allow the number of shocks to be reduced while improving the comminution process.

Phase II

Contract Number: 9105186
Start Date: 00/00/00    Completed: 00/00/00
Phase II year
1991
Phase II Amount
$225,000
Medical instrumentation, lithotripsy, shock waves extracorporeal shock wave lithotripsy (eswl) has become the preferred method of removal for the majority of symptomatic renal, ureteral, and biliary calculi. Recently, medical research has revealed that eswl can cause a variety of acuteand possibly chronic injuries. The propagation and focusingof shock waves in, and their interaction with, tissue and calculi is sufficiently complex that the aspects of the pressure field contributing to injury and to stone fragmentation cannot yet be identified. The main objective of the research is to gain fundamental knowledge of the properties of convergent shock waves in tissues, and their interaction with stone materials. A concomitant objective is to employ the knowledge so gained to assess the feasibility of developing instrumentation to both diagnose and control the lithotripsy process. Polyvinylidene fluoride pressure transducers will be used toacquire shock pressure and scattered wave data. The data will be used in conjunction with numerical shock dynamics calculations to understand the propagation process and in developing an empirical scattering model. It is anticipatedthat it will be possible to predict key elements of the interaction process by the use of innovative algorithms and to use the algorithms as a basis for new lithotripter instrumentation.