SBIR-STTR Award

Care Assistant for Family Caregivers of Persons with Dementia During Out of the Home Activities
Award last edited on: 2/14/2024

Sponsored Program
SBIR
Awarding Agency
NIH : NIA
Total Award Amount
$1,677,801
Award Phase
2
Solicitation Topic Code
866
Principal Investigator
Shane M Anderson

Company Information

Koronis Biomedical Technologies Corporation (AKA: KBTC~KBT)

861 East Hennepin Avenue Unit 410
Minneapolis, MN 55414
   (763) 447-6115
   info@koronisbiotech.com
   www.koronisbiotech.com
Location: Single
Congr. District: 05
County: Hennepin

Phase I

Contract Number: 1R43AG058336-01A1
Start Date: 8/1/2018    Completed: 7/31/2019
Phase I year
2018
Phase I Amount
$224,823
Increases in life expectancy together with demographic trends have fueled a rapid increase in America's elderly population. As the number of older Americans has grown, so has the prevalence of aging-associated diseases, including Alzheimer's Disease (AD) and dementia. An estimated 5.4 Million Americans had AD in 2012, that number is expected to double by 2030. It is estimated that most these patients (70%) live at home where they receive 75% of their care from informal caregivers, unpaid individuals such as family members, friends, and neighbors. The natural progression of the disease and its burdensome behaviors cause significant stress for caregivers who frequently have close relationships to the patient. Among caregivers of dementia patients, wandering behavior is one of the most stress-provoking symptoms. Wandering is a common symptom that encompasses various walking behaviors that can result in the patient becoming lost or disoriented leading to the risk of serious injury or death for the patient and stress and reduced independence for the caregiver. Family caregivers often cannot leave patients home alone, and instead must bring them on errands to large complex indoor environments. Koronis Biomedical Technologies will develop a prototype patient tracking solution that will give peace of mind to caregivers in both stationary and mobile scenarios, alerting the caregiver to wandering behavior and allowing them to quickly locate their loved one. It will consist of a monitoring system that features geo-fencing and tether modes for both indoor and outdoor use. Feasibility and usability of the prototype system will be assessed by family caregivers through a series of focus groups, as well as engineering evaluations.

Public Health Relevance Statement:
Narrative Informal and family caregivers provide three quarters of the care for America's dementia population at a great economic and emotional cost to themselves. These caregivers experience significant stress due to the burdensome behaviors associated with dementia. A significant source of stress is associated with a common disease behavior known as wandering or elopement. The proposed research seeks to develop a comprehensive caregiver tracking assistant device to reduce these burdens, and to facilitate greater caregiver independence.

Project Terms:
Elderly; senior citizen; older person; older adult; later life; late life; geriatric; elders; advanced age; Aging; Alzheimer's Disease; senile dementia of the Alzheimer type; primary degenerative dementia; dementia of the Alzheimer type; Primary Senile Degenerative Dementia; Alzheimers disease; Alzheimers Dementia; Alzheimer's; Alzheimer syndrome; Alzheimer sclerosis; Alzheimer disease; Alzheimer Type Dementia; Alzheimer; Americas; Behavior; Communities; Cessation of life; Death; Diagnosis; Disease; Disorder; Economics; Engineering; Environment; Family; Feedback; Focus Groups; Health care facility; care facilities; Healthcare Facility; Health Facilities; Human; Modern Man; Life Expectancy; Minnesota; Nursing Staff; nursing personnel; Patients; Research; Residential Treatment; residential care; Risk; School Nursing; School Health Nursing; Self-Help Devices; assistive device; Assistive Technology; Stress; Technology; Time; Transportation; Universities; Visual impairment; visually impaired; vision impairment; impaired vision; Subnormal Vision; Reduced Vision; Partial Sight; Low Vision; Diminished Vision; Friends; Walking; Caregivers; Care Givers; Family Caregiver; Family Care Giver; Family member; Caring; Injury; base; improved; Area; Phase; psychological; psychologic; Series; Evaluation; Disorientation; Individual; Disease Progression; Impaired cognition; cognitively impaired; cognitive loss; cognitive dysfunction; Disturbance in cognition; Cognitive function abnormal; Cognitive decline; Cognitive Impairment; Cognitive Disturbance; Notification; Hour; Complex; Home environment; Home; Source; System; Location; Dementia; Amentia; Services; Medical center; American; experience; Performance; professor; peace; Devices; Positioning Attribute; Position; Biomedical Technology; Emotional; Caregiver Burden; caregiver stress; care giver stress; Care giver Burden; Cellular Phone; smartphone; smart phone; iPhone; Cellular Telephone; Cell Phone; Radio; Symptoms; Doctor of Philosophy; PhD; Ph.D.; wireless; Wireless Technology; Monitor; trend; cost; blind; Population; Prevalence; Mind; wi-fi; wireless fidelity; usability; prototype; loved ones; Indoor environment; informal care; Informal care giver; informal caregiver; dementia care giver; Dementia caregivers; Care giver support; Caregiver support; cloud server; cloud platform; common symptom; iPhone Application; iPhone App; iOS application; iOS app; Smartphone App; Smart Phone Application; Smart Phone App; Cellular Phone Application; Cellular Phone App; Cell phone App; Cell Phone Application; Android Application; Android App; smartphone Application; Bluetooth

Phase II

Contract Number: 2R42AG058336-02A1
Start Date: 8/1/2018    Completed: 8/31/2025
Phase II year
2022
(last award dollars: 2023)
Phase II Amount
$1,452,978

Increases in life expectancy together with demographic trends have fueled a rapid increase in America's elderly population. As the number of older Americans has grown, so has the prevalence of aging-associated diseases, including Alzheimer's Disease (AD) and other related dementias (ADRD). An estimated 5.4 Million Americans had AD in 2012, and that number is expected to double by 2030. It is estimated that most of these patients (70%) live at home where they receive 75% of their care from informal caregivers who are unpaid individuals such as family members, friends, and neighbors. The natural progression of the disease and its burdensome behaviors cause significant stress for caregivers who frequently have close relationships to the patient. Among caregivers of dementia patients, wandering behavior is one of the most stress-provoking symptoms. Wandering is a common symptom that encompasses various walking behaviors that can result in the patient becoming lost or disoriented leading to the risk of serious injury or death for the patient and stress and reduced independence for the caregiver. Family caregivers often cannot leave patients home alone, and instead must bring them on errands to large and complex indoor environments which present additional risk for an AD patient to wander. Koronis Biomedical Technologies will develop a tracking solution that will give peace of mind to caregivers in both stationary and mobile scenarios, alerting the caregiver to wandering behavior and allowing them to quickly locate their loved one. It will consist of a monitoring system that features geo-fencing and wireless tether modes for both indoor and outdoor use. Efficacy of the proposed system will be assessed by family caregivers through a pilot clinical study, as well as through engineering evaluations.

Public Health Relevance Statement:
Narrative Informal and family caregivers provide three quarters of the care for America's dementia population at great economic and emotional cost to themselves. These caregivers experience significant stress due to the burdensome behaviors associated with dementia. A significant source of stress is associated with a common disease behavior known as wandering or elopement. The proposed research seeks to develop a comprehensive caregiver tracking assistant device to reduce these burdens, and to facilitate greater caregiver independence.

Project Terms:
Elderly; advanced age; elders; geriatric; late life; later life; older adult; older person; senior citizen; Aging; Alzheimer's Disease; AD dementia; Alzheimer; Alzheimer Type Dementia; Alzheimer disease; Alzheimer sclerosis; Alzheimer syndrome; Alzheimer's; Alzheimer's disease dementia; Alzheimers Dementia; Alzheimers disease; Primary Senile Degenerative Dementia; dementia of the Alzheimer type; primary degenerative dementia; senile dementia of the Alzheimer type; Americas; Behavior; Clinical Research; Clinical Study; Clinical Trials; Cessation of life; Death; Disease; Disorder; Economics; Engineering; Environment; Feedback; Focus Groups; Human; Modern Man; Lead; Pb element; heavy metal Pb; heavy metal lead; Life Expectancy; Long-Term Care; extended care; longterm care; Minnesota; Persons; Patients; Research; Risk; Public Health Schools; Assistive Technology; assisted device; assistive device; Self-Help Devices; Stress; Technology; Phone; Telephone; Testing; Transportation; Universities; Visual impairment; Diminished Vision; Low Vision; Partial Sight; Reduced Vision; Subnormal Vision; vision impairment; visually impaired; Friends; Walking; Caregivers; Care Givers; Family Caregiver; Family Care Giver; Family member; Caring; Injury; injuries; base; Area; Phase; psychologic; psychological; Evaluation; Disorientation; Individual; Disease Progression; Funding; Companions; Cognitive Disturbance; Cognitive Impairment; Cognitive decline; Cognitive function abnormal; Disturbance in cognition; cognitive dysfunction; cognitive loss; Impaired cognition; Notification; Hour; Complex; Source; System; Location; Amentia; Dementia; Consult; Services; Medical center; American; experience; professor; Participant; peace; Devices; Position; Positioning Attribute; Biomedical Technology; Emotional; Care giver Burden; Caregiver Burden; miniaturize; Cell Phone; Cellular Telephone; iPhone; smart phone; smartphone; Cellular Phone; Radio; Symptoms; Ph.D.; PhD; Doctor of Philosophy; Monitor; trend; Development; developmental; cost; efficacy evaluation; efficacy analysis; efficacy assessment; efficacy examination; evaluate efficacy; examine efficacy; nanodevice; nano device; efficacy trial; human study; blind; Population; Prevalence; Mind; wireless fidelity; wi-fi; usability; Alzheimer's disease risk; Alzheimer risk factor; alzheimer risk; prototype; loved ones; new product development; cloud based; Indoor environment; informal care; informal caregiver; Informal care giver; Dementia caregivers; dementia care giver; common symptom; smartphone Application; Android App; Android Application; Cell Phone Application; Cell phone App; Cellular Phone App; Cellular Phone Application; Smart Phone App; Smart Phone Application; Smartphone App; iOS app; iOS application; iPhone App; iPhone Application; Bluetooth; real time monitoring; realtime monitoring; Alzheimer's disease patient; Alzheimer's patient; Alzheimer's disease caregiver; Alzheimer's care giver; Alzheimer's caregiver; Alzheimer's dementia care giver; Alzheimer's dementia caregiver; Alzheimer's disease care giver; Home; wireless; caregiver stress; care giver stress