SBIR-STTR Award

Hormonal Therapeutic for Retinopathy of Prematurity
Award last edited on: 11/10/2017

Sponsored Program
SBIR
Awarding Agency
NIH : NEI
Total Award Amount
$224,700
Award Phase
1
Solicitation Topic Code
W
Principal Investigator
Tammy Z Movsas

Company Information

Zietchick Research Institute LLC

46701 Commerce Center Drive
Plymouth, MI 48170
   (989) 430-7437
   N/A
   N/A
Location: Single
Congr. District: 11
County: Wayne

Phase I

Contract Number: ----------
Start Date: ----    Completed: ----
Phase I year
2017
Phase I Amount
$224,700
Whenever premature birth interrupts normal retinal vascularization of the developing eye, retinopathy of prematurity (ROP) can occur. When ROP was first reported in the 1940’s, it was associated with high, oxygen delivery to preterm infants. Though oxygen delivery to preterm infants is now carefully regulated, ROP is still a common occurrence. In very low birthweight infants (birth weights

Public Health Relevance Statement:
Retinopathy of prematurity (ROP), diagnosed in 25% of very low birth weight (VLBW) infants, (birth weights

Project Terms:
advanced disease; Anterior; Archives; Award; base; biobank; Birth; Birth Weight; Blindness; Blood; Blood Vessels; Cells; Child; Childhood; Chorionic Gonadotropin; Data; deprivation; Development; Diagnosis; disability; Disease; Dose; Exposure to; Eye; Eye Development; Eye diseases; Eyedrops; falls; fetal; Glaucoma; Gonadotropins; Grant; Harvest; Health; Hormonal; Hormone Receptor; Hormones; Human; Human Chorionic Gonadotropin; in utero; Incentives; Incidence; Infant; Interruption; intraperitoneal; Ischemia; Knockout Mice; laser photocoagulation; Legal patent; LH Receptors; Life; Light Coagulation; Low Birth Weight Infant; Luteinizing Hormone; Marketing; Measures; Medical; Michigan; Mission; Molecular Weight; Mus; Neonatal; neonate; neovascular; Newborn Infant; novel; novel therapeutics; Oxygen; Pathogenesis; Pathologic; Pathway interactions; Phase; Physiological; Placental Hormones; Posterior eyeball segment structure; postnatal; pre-clinical; preclinical efficacy; Premature Birth; Premature Infant; prevent; Prevention; Preventive; Production; Rare Diseases; Rattus; Reaction; Reporting; reproductive hormone; Research; research clinical testing; Research Institute; Retina; retina blood vessel structure; Retinal; retinal angiogenesis; Retinal Detachment; Retinal Diseases; retinal ischemia; Retinal Neovascularization; Retinopathy of Prematurity; Risk; Role; safety study; Sampling; Science; Signal Transduction; Small Business Innovation Research Grant; Spottings; Strabismus; theories; Therapeutic; Time; Uterus; Vascular Endothelial Growth Factors; Vascularization; Very Low Birth Weight Infant; Visual; Vitrectomy; Work

Phase II

Contract Number: ----------
Start Date: ----    Completed: ----
Phase II year
----
Phase II Amount
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