The purpose of this proposal is to develop a protein assay technology that will parallel the newly developing oligonucleotide microarray techniques. We will develop a peptide system capable of performing high throughput real time measurements in parallel on a microfluidic chip. We will develop the chemistry to prepare these chips in Phase I and develop the system using these chips in a biologically important application in Phase II.
Thesaurus Terms: high throughput technology, microprocessor /microchip, peptide, technology /technique development drug screening /evaluation, miniature biomedical equipment, peptide chemical synthesis, protein protein interaction biotechnology, high performance liquid chromatography, mass spectrometry, nuclear magnetic resonance spectroscopy, polymerase chain reaction
