DESCRIPTION (Abstract of Application): Early-onset esotropia is one of the most prevalent of clinically important eye disorders in infants and children. Yet its origins remain poorly understood and clinical treatment less than optimum. Study of binocular vision is an important tool to study both esotropia's origins and methods to improve treatment. However, extant binocular vision test techniques require the infant to wear some form of stereo glasses or goggles, which are distracting and thus may reduce testability of this already difficult-to-test population. Response measures in infant studies to date have usually been based either on forced-choice preferential looking, which typically requires attention for extended testing, that again, may reduce testability, or on electro-oculogram eye movement measures, which require attachment of electrodes that may be distracting or not acceptable to the parents and thus, yet again, reduce testability. The system to be constructed under the present revised proposal is comprised of a new type of autostereoscopic display, based on a standard liquid crystal display computer monitor, that provides stereo or other haploscopic display without need of stereo goggles or glasses. Response measurement is by means of a new video tracker that will track both head and eye motion.National Eye Institute (NEI)
