Surgeons performing arthroplasty on painful, misshapen, arthritic hand joints do not have the choice of replacing the damaged joint with a prosthesis that will restore near natural movement as they would if a hip joint were being replaced. There are no effective finger joint replacements available. Past attempts to produce hinge type joints have failed because the minute pin of the hinge bore all the load placed on the finger leading to its early breakdown. The innovative Arthroflex concept is based on the fact that little load is applied when the fingers are moving. When a load is applied, there is little or no movement. By mounting the pin elastically, loading will cause large mating surfaces on the rigid stems to come in contact, thus taking the load off the pin. This research is to demonstrate feasibility of the Arthroflex concept. Kinematic and finite element analysis (FEA) will be used to analyze forces on joints during normal hand usage. Test data to be produced will be incorporated in the FEA program to formulate the ultimate mechanical design for prototype development and clinical testing during Phase II.Awardee's statement of the potential commercial applications of the research: Successful outcome of this research will solve a critical problem of finger joint arthroplasty which could result in Arthroflex sales of $ 100,000,000 in seven to ten years. When applied to other small joint replacements, the sales would be substantially more.National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)