SBIR-STTR Award

Positron tomograph using optical coupled detectors
Award last edited on: 4/15/02

Sponsored Program
SBIR
Awarding Agency
NIH : NCI
Total Award Amount
$550,000
Award Phase
2
Solicitation Topic Code
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Principal Investigator
Gerd Muehllehner

Company Information

UGM Medical Systems Inc

3611 Market Street
Philadephia, PA 19104
   (215) 222-5701
   N/A
   N/A
Location: Single
Congr. District: 03
County: Philadelphia

Phase I

Contract Number: 1R43CA052342-01
Start Date: 00/00/00    Completed: 00/00/00
Phase I year
1990
Phase I Amount
$50,000
It has been demonstrated that a high-resolution positron emission tomograph can be constructed using six large-area position-sensitive sodium iodide NaI (T1) scintillation detectors. This research addresses a basic modification to the detection system that will result in significant performance improvements and a reduced system cost Specifically, it is planned to optically couple the system's detectors, enabling scintillation light to be shared by neighboring detectors. This eliminates the sharp boundaries between detectors, which will reduce the size of the effective gap between detectors, resulting in improved image quality. This should also permit substitution of a reduced number of larger round photomultipliers for the current rectangular array of the more expensive square photomultipliers. Phase I efforts will investigate techniques for optically coupling the detectors, techniques for position estimation near the boundaries of two optically coupled detectors, and the adaptation of the event-triggering system for use with optically coupled detectors. Phase II research will concentrate on incorporating the optically coupled detector system into a tomographAwardee's statement of the potential commercial applications ofthe research: This research will result in improved performance and lower cost of the current hexagonal positron emission tomograph produced by UGM Medical Systems, Inc. This will make the system even more ideally suited for clinical nuclear medicine applications such as the diagnosis of brain disorders or the assessment of myocardial viability than the currently available systemNational Cancer Institute (NCI)

Phase II

Contract Number: 2R44CA052342-02
Start Date: 00/00/00    Completed: 00/00/00
Phase II year
1991
(last award dollars: 1992)
Phase II Amount
$500,000

The objective of this grant is the construction and evaluation of a Positron Emission Tomograph (PET) with a large axial field of view of 20-25 cm. This device will be ideally suited for whole body surveys necessary in the detection and staging of metastatic tumors; it will have twice the field of view and four times the sensitivity of current state-of-the-art PET scanners. This performance improvement possible it will be necessary to implement and evaluate a fully three-dimensional reconstruction algorithm. Preliminary results indicate that this algorithm will not only improve the image quality but it will also be possible to implement it given existing technology with clinically acceptable reconstruction times.Awardee's statement of the potential commercial applications of the research:There is widespread agreement that timor imaging will represent the most important clinical application for PET imaging, even surpassing cardiac imaging within the next few years. This device is ideally suited for this emerging clinical need, providing both high sensitivity and a large axial field of view.National Cancer Institute (NCI)