The objective of this project is the commercial development of systems for application to human cancer treatment with locoregional hyperthermia. The scope of the -research includes the design of ultrasonic and magnetic induction devices (applicators) in order to determine feasibility and cost estimates for Phase 11 development of prototypes. In addition to the research into the design of the energy deposition applicators, a multifunction microprocessor system will be designed to control the function of the above applicators as well as interfaces to interstitially implanted electrodes also used for tumor temperature elevation. The latter type of energy deposition is given lower priority because it is an invasive procedure usually requiring surgical intervention, whereas the other methods are noninvasive. The multifunction controller will optimize the operation of the applicators, control tumor temperature, and function as the temperature measuring system. This latter system will have serial communications links to the controller as well as standalone capabilities and the capability to yield artifact free data in high radio frequency fields without the problem of field perturbation.National Cancer Institute
