This research is developing a periodontal probe using a Laser Doppler Velocimeter Capillary Perfusion Monitor to provide a quantitative means of relating periodontal disease to blood flow and perfusion in the pocket of the diseased gingiva. Current methods, such as measurements of pocket depth, attachment level, and evidence of bleeding on probing, are unreliable and not correlated strongly with disease. An urgent research need is for the development of more accurate and reliable methods of assessing periodontal disease. A noninvasive method that can be used to test the efficacy of experimental treatments in relatively short time intervals is highly desirable.The Phase I effort is expected to result in a prototype noninvasive probe and preliminary data regarding ease of use and sensitivity, and preliminary data regarding ease of use and sensitivity, and preliminary numerical data on an animal model. The probe will be tested by a dental researcher who will assist in the evaluation and provide suggestions for improvements for Phase 11.The probe could be used by dental researchers and later by clinicians when the relationships between laser Doppler probe measurements and periodontal disease are established.National Institute Of Dental Research
