SBIR-STTR Award

Multi-Modal Neurodiagnostic Tool for Exploration Missions
Award last edited on: 10/20/2015

Sponsored Program
SBIR
Awarding Agency
NASA : JSC
Total Award Amount
$849,877
Award Phase
2
Solicitation Topic Code
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Principal Investigator
Yong Jin Lee

Company Information

Linea Research Corporation

1020 Corporation Way Suite 216
Palo Alto, CA 94303
   (650) 325-9000
   info@linearesearch.com
   www.linearesearch.com
Location: Single
Congr. District: 16
County: Santa Clara

Phase I

Contract Number: ----------
Start Date: ----    Completed: ----
Phase I year
2011
Phase I Amount
$100,000
NASA has a requirement for a neurodiagnostic tool that can be used to monitor the behavioral health of the crew during long duration Exploration missions. The device should unobtrusively monitor and detect neurophysiological markers of stress that could lead to behavioral or performance deterioration. The neurodiagnostic monitor should be lightweight and compact and should require minimal time or effort for the crew to use. Among the various neurodiagnostic modalities, electroencephalography (EEG) and functional near infrared spectroscopy (fNIRS) are most amenable for integration into a lightweight, wearable system that can be adapted for use in Space. We will demonstrate the feasibility of a wearable multi-modality neurophysiological device for monitoring stress. The wearable monitoring system will provide a real-time functional imaging of cortical activity while the crew performs Exploration mission activities.

Phase II

Contract Number: ----------
Start Date: ----    Completed: ----
Phase II year
2013
Phase II Amount
$749,877
NASA has a critical requirement for a neurodiagnostic tool that can be used to monitor the behavioral health of the crew during long duration exploration missions. The device should unobtrusively monitor and classify neurophysiological markers associated with decrements in behavioral state and cognition. The neurodiagnostic monitor should be lightweight and compact and should require minimal time or effort for the crew to use. The device should be unobtrusive enough to allow mission operations to be performed during monitoring. In Phase 1 of the program, we were able to successfully monitor cortical activity using multi-parameter sensor modules. In addition to electroencephalography (EEG) and functional near infrared spectroscopy (fNIRS) signals that provided the electrophysiological and cortical oxygenation information, we were able to obtain photoplethysmography (PPG) and electrooculography (EOG) signals to compute the heart rate and frequency of eye movement. In Phase 1 we also demonstrated the functionality of an algorithm that automatically classifies the varying degrees of cognitive loading based on the measured physiological parameters. In the proposed Phase 2 program, we will develop a flight-capable neurodiagnostic device that can be unobtrusively worn on the head. Based on the neuro and non-neurophysiological parameters obtained from the multi-modality sensors, we will detect and classify neurophysiological markers associated with decrements in behavioral state and cognition. We will develop an automated algorithm that can recognize and identify key decrements in behavioral state.