There is a need for a portable detector system that can detect illegal drugs, primarily marijuana, cocaine, and heroin, entering the United States aboard maritime vessels. A preliminary investigation has shown that SAW technology can detect 10 femtograms (1 x 10-14) with a signal to noise ratio of 3:1. In addition, these sensors have a dynamic range of over 1,000,0-00. By combining SAW technology with fast chromatography, femtogram sensitivity and low false alarm rate ( 1%) can be achieved. A portable instrument capable of taking samples from the open environment or sealed containers is proposed. The objective of the Phase I effort will be to theoretically predict and experimentally measure the sensitivity of SAW sensors to marijuana, cocaine and heroin. Based upon these experiments, a prototype drug detection system will be designed and constructed during Phase II. The advantages of the proposed approach are: (1) the instrument is based on an innovative combination of fast chromatography and SAW sensor technology, (2) construction is based upon small size and low power solid-state components, and (3) the drug detection system can be portable real-time, and low cost.Anticipated Results/Potential Commercial Applications Of Results:The end product of the Phase I program will be a design for a prototype real-time instrument for the detection of drugs. The development of a portable, highly sensitive instrument for the detection of illicit drugs has direct application to the commercial market in the area of state and local enforcement agencies.