SBIR-STTR Award

This goal is to construct a low-cost, polymeric, nanomaterial-based assay for the detection of multiple biological agents in a single device using our nanomanipulation technology to meet or exceed the sensitivity of the current two-line assays used in DoD applications. The nanodevice will exhibit no background streaking, cross bleeding, or other flow problems often associated with laminar flow devices. We expect to demonstate a multiplex device capable of detecting between 5 and 8 biothreat agents

We propose to continue the development of rapid, handheld multiplexed assays for the detection of biological warfare agents and an associated handheld automatic reader. We will rigorously evaluate the 5-target assay developed in Phase I, and develop an 8-target multiplex during this Phase II project. The handheld automatic reader will undergo further modification and improvements to provide for the 8 target multiplexed assay.

Keywords:
Multiplexed Assay, Bioagent Detection, Nanomaterial,