We intend to develop and test a non-invasive, cost-effective method for breast cancer screening. The technology involves the scanning of electrical signals from the breast surface. The specific aims are to develop the hardware and software for such an application and to test the method on representative groups of the breast patient population. If the feasibility of this method can be demonstrated during Phase I, we will demonstrate efficacy under a more comprehensive breast screening protocol in Phase II.Awardee's statement of the potential commercial applications of the research:This technology has the potential to provide a non-invasive, cost-effective means of breast cancer screening. The device would be less expensive than mammography equipment, and would be affordable by the office-based physician. The test could become part of a routine checkup in the primary care office.National Cancer Institute (NCI)