In order to limit the spread of contamination and restore combat operations, CBBD is requesting the development of a man-portable system which rapidly decontaminates items, such as sensitive equipment, etc. The decontamination system will be effective against a broad spectrum of biological agents (spores, bacteria, and virus) within minutes. The decontamination efficacy should be 99.9 percent reduction of biological agents with an objective of 99.9999 percent deactivation of detectable pathogens. To achieve this goal, CBD has identified a man-portable, cold plasma (atmospheric pressure plasma) as a viable decontamination system. The plasma source should be < 40 lbs, able to decontaminate the model system (such as a handheld radio) within 10 minutes, be able to run for 1 hr on battery power, and be able to run on external power. During Phase I, Triton Systems proposes to demonstrate the proof-of-principle by constructing a breadboard prototype that achieves the necessary conditions to decontaminate a model system within 10 minutes. Triton will demonstrate the effectiveness of the system on two representative test coupons: a metal surface and a polycarbonate surface. The coupons will be contaminated with a broad spectrum of biological weapon surrogates (from bacteria, viruses, and spores) to demonstrate the deactivation/kill efficacy of the breadboard system. From these proof-of-principle experiments, Triton will demonstrate that the required performance parameters can be achieved during Phase II. In Phase II, Triton will refine the design and construct a brass-board prototype that provides the form, fit and function of the targeted end-product. The prototype will include management of effluents to ensure agents or harmful chemicals are contained during the decontamination process.