Pelican Therapeutics Inc, spun out of SBIR firm Heat Biologics in 2012 and then acquired by Heat Biologics in 2017 and now operating as a subsidiary of Heat Biologics, develops immunotherapeutics for the stimulation of CD8+ T cells for cancer treatment. The company's two primary product candidates are both T cell activation therapeutics, PTX-35 and PTX-45, and have achieved in vivo regulatory T cell expansion in humans.