Company Profile

Theracos Inc
Profile last edited on: 11/2/20      CAGE: 47B04      UEI:

Business Identifier: Research programs in inflammation, metabolism and depression
Year Founded
2000
First Award
2005
Latest Award
2006
Program Status
Inactive
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Location Information

225 Cedar Hill Street Suite 200
Marlborough, MA 01752
   (508) 688-4221
   info@theracos.com
   www.theracos.com
Location: Single
Congr. District: 03
County: Middlesex

Public Profile

Theracos, Inc. is a pharmaceutical research and development company which develops novel therapeutic agents for diseases with significant unmet medical need. It currently has five internal development programs underway in three therapeutic areas: metabolism, inflammation, and psychiatry. The most advanced program, entering Phase II clinical trials, is directed toward the treatment of type 2 diabetes. The company is developing a series of SGLT2 inhibitors as a potential drug to treat type 2 diabetes. It is reported that the process works by inhibiting the kidney’s ability to recover glucose that’s been excreted – thereby increasing the amount that is shed in urine, and decreasing the amount retained in the blood. The company is also reporte as recruiting participants with type 2 diabetes for a Phase 2b dosing trial. The firm's experimental drug - bexagliflozin - has been tested in studies in the U.S., Europe, Russia and Japan. It is reported as working in a similar manner to Farxiga, a type 2 diabetes drug developed by AstraZeneca and approved in 2014 that also works as an SGLT2 inhibitor. Other such drugs are Invokana and Jardi

Extent of SBIR involvement

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Synopsis: Awardee Business Condition

Employee Range
15-19
Revenue Range
1.5M-2M
VC funded?
Yes
Public/Private
Privately Held
Stock Info
----
IP Holdings
15-19

Awards Distribution by Agency

Most Recent SBIR Projects

Year Phase Agency Total Amount
2006 1 NIH $100,000
Project Title: THR-0921 for Cardiovascular Complications of Diabetes
2005 1 NIH $100,000
Project Title: Novel PPAR alpha/gamma Agonist for Type 2 Diabetes

Key People / Management

  Edward P Amento -- Founder and President

  Albert R Collinson -- President & CEO