SBIR-STTR Award

Evidence-Based Evaluation Process for Traumatic Brain Injuries and Co-morbid Psychological Disorders in Service Members
Award last edited on: 11/13/2013

Sponsored Program
SBIR
Awarding Agency
DOD : DHA
Total Award Amount
$849,980
Award Phase
2
Solicitation Topic Code
OSD09-H07
Principal Investigator
David E Weldon

Company Information

JXT Applications Inc

1195 Meadow Bridge Drive Suite C
Beavercreek, OH 45434
   (937) 431-1566
   N/A
   www.jxtai.com
Location: Single
Congr. District: 10
County: Green

Phase I

Contract Number: ----------
Start Date: ----    Completed: ----
Phase I year
2010
Phase I Amount
$99,999
Mild traumatic brain injury (mTBI) is strongly associated with emotional and physical health problems, of which PTSD and depression are important mediators. There is a significant overlap between of military members who have experienced and/or witnessed a life threatening event and sustained a blast or other TBI. There is a need to develop a user-friendly, empirically-based, neuropsychological screening tool to be used by first responders to screen for mTBI. In Phase I, JXT will assess the co-occurrence of these neurocognitive and emotional events, determine the problems and associated conditions, examine the long term implications and evaluate diagnostic instruments in order to distinguish who is most at risk for becoming impaired. From this information, JXT will identify a pool of neuropsychological and emotional health test items to be used to construct a Statistical and Evidence-Grounded mTBI Evaluation and Neuro-assessment (SEGMEN) Tool; identify and document important control and mediator variables; specify the criterion/outcome variables; and prepare to evaluate the reliability and validity of the SEGMAN Tool in Phase II. This effort will be driven by the innovative JXT Test Construction and Validation Process Model. We will also create an automated conceptual demonstration of the SEGMEN Tool to assess usability and commercial potential.

Keywords:
Mild Traumatic Brain Injury; Mtbi; Tbi Screening; Mtbi Screening; Neuropsychological Assessment; Brain Injury; Traumatic Brain Injury; Tbi

Phase II

Contract Number: ----------
Start Date: ----    Completed: ----
Phase II year
2011
Phase II Amount
$749,981
Mild traumatic brain injury (mTBI) is associated with emotional and physical health problems, of which PTSD and depression are important mediators. Our Phase I research created a conceptual model for a user-friendly, empirically-based screening/tracking tool available to first responders and medical practitioners to screen for mTBI or other disorders. We assessed the co-occurrence of these co-morbid disorders with mTBI, determined the associated conditions, examined the implications, and evaluated diagnostic instruments that distinguish who is most at risk of impairment. From this information, JXT identified a pool of neuropsychological, neurological, physiological, and other test instruments for inclusion in a Statistical and Evidence-Grounded mTBI Evaluation and Neuro-assessment (SEGMEN) Tool. We documented important control and mediator variables; specified outcome variables; and prepared to evaluate the SEGMEN Tool in Phase II. This effort was driven by the innovative JXT Test Construction and Validation process model. We also created a conceptual demonstration of the SEGMEN Tool to assess usability and commercial potential. In Phase II, we will execute numerous, retrospective validation studies of the pool of test instruments, select the most powerful discriminators, and install them in a SEGMEN Tool prototype that can operate in stand-alone mode or integrated with Military Medical Systems located anywhere.

Keywords:
Mild Traumatic Brain Injury; Mtbi; Tbi Screening; Mtbi Screening; Neuropsychological Assessment; Brain Injury; Traumatic Brain Injury; Tbi