Tech Seeker (TS)

NewLink Genetics Corporation (AKA:New Link Genetics Inc~NewLink~BioProtection Systems Corp)
Profile last edited on: 6/20/13

Cancer vaccines and drugs that modulate the immune system
TS Type
Small Corporation
Status
Inactive
Year Founded
1999
Last Involved Year
N/A

Key People / Management

  Kenneth R Lynn --

Location Information

2901 South Loop Drive Suite 5100
Ames, IA 50010
   (515) 296-5555
   www.newlinkgenetics.com

Public Profile

Headquartered in Ames, IA but with facilities in Devens MA and Austin, TX, NewLink Genetics Corporation, a biopharmaceutical company, focuses on immunotherapeutic products for the treatment of cancer. The firm's portfolio includes biologic product candidates based on its HyperAcute cellular immunotherapy technology, which is designed to stimulate the human immune system to attack cancer cells; and small-molecule product candidates that are focused on breaking the immune system's tolerance to cancer by inhibiting the indoleamine-2, 3-dioxygenase pathway and the tryptophan-2, 3-dioxygenase pathway. The company is developing IDO pathway inhibitors comprising indoximod that is in multiple Phase I and Phase II clinical trials for patients with melanoma, pancreatic cancer, malignant brain tumors, metastatic breast cancer, acute myeloid leukemia, prostate cancer, and non-small cell lung cancer (NSCLC); and GDC-0919 and atezolizumab (MPDL3280A) that is in Phase Ib clinical trials for patients with locally advanced or metastatic solid tumors. Its clinical development products include NLG2101 for metastatic breast cancer; NLG2102 for refractory malignant brain tumors; NLG2103 for advanced melanoma; NLG2104 for metastatic pancreatic cancer; NLG2105 for pediatric patients with refractory malignant brain tumors; and NLG2106 for acute myelogenous leukemia. The company?s HyperAcute cellular immunotherapy product candidates under clinical development include tergenpumatucel-L, is being investigated in Phase Ib/II clinical trial for patients with advanced NSCLC; and dorgenmeltucel-L, is being investigated in a Phase II clinical trial for patients with advanced melanoma. Its infectious disease program includes replication-competent recombinant vesicular stomatitis virus, a vaccine technology to treat Ebola and Marburg viruses.

Extent of SBIR involvement

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Synopsis: Techseeker Business Condition

Headquartered
USA
Employment
125
Revenue
N/A
Public/Private
Publicly Traded
Stock Info
NASDAQ : NLNK
Received SBIR $$
Yes

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