Date: Apr 13, 2016 Author: Gary Seller Source: (
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CASIS Announces Series of New Research Awards in Areas of Earth Observation, Education, Physical and Life Sciences
Investigation: Comparative Real-Time Metabolic Activity Tracking for Improved Therapeutic Assessment Screening Panels
490 Biotech's reporter-gene system for substrate-free bioluminescent human cell lines is an enabling technology for the evaluation of drug safety and effectiveness. Cellular response to drug samples is observable via visible data acquisition in both tissues and small animal models. The microgravity environment on-board the ISS promotes superior 3D cell growth conditions, enabling evaluations (using this cell line) that may better mimic the cellular response of human tissues. This investigation will specifically examine anticancer therapeutics with downstream applications for other drugs with hopes to validate a novel bioluminescent assay tool kit that may significantly reduce the failure rate and high development cost of current drug discovery efforts.