With direct ties to Case Western - and itself spinning out of another Case Western start-up (NDI) - SPR Therapeutics, LLC develops and commercializes interventional pain management therapies and medical devices. With their capabilities designated the SPRINT® PNS System, the firm offers a breakthrough treatment designed to "recondition' the central nervous system for significant and sustained relief from chronic pain. Describing themselves as a medical device company developing peripheral nerve stimulation products for pain management clinicians, the firm is organized around the concept of neurostimulation targeting peripheral nerves with the effort being to provide an alternative to spinal cord stimulators for the treatment of chronic pain. The company's primary product is Smartpatch, a percutaneous peripheral nerve stimulation (PNS) system for post-surgical pain following surgeries. The device has applications for operations in knee replacement, thoracotomy, rotator cuff repair; neuropathic pain, nerve surgery, phantom limb pain, and musculoskeletal pains. The firm's products also include Smartpatch short-term therapy for sustained relief; Micropulse long term therapy through implantable PNS system; and Smartpatch MicroLead, which includes a coiled wire construction that fosters rapid tissue ingrowth.