Company Profile

Atrapos Therapeutics LLC
Profile last edited on: 12/8/17      CAGE: 7FD24      UEI: XSPNBFMNCKD4

Business Identifier: NO Business Identifier is currently available for this company.
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Location Information

3900 Essex Lane Suite 575
Houston, TX 77027
   (713) 341-1198
Location: Single
Congr. District: 07
County: Harris

Public Profile

Atrapos Therapeutics is developing targeted immunomodulatory therapeutics for management to diseases with inappropriate immune responses. The company is targeting STAT6 which is an important player in the pathway involved in TH2 immune cells involved in several disease settings. The module has demonstrated encouraging activity in animal models of allergic asthma and is currently being evaluated in other therapeutic settings. STAT6 is a messager molecule found in T helper lymphocytes (TH2 cells, a type of immune cell) In response to cytokines and growth factors, STAT family members ar (1) phosphorylated by the receptors associated kinases, and then form homo or heterosimers that translocate to the cell nucleus where they act as transcription activators. This protein play central role in t exerting IL4 mediated biological responses.TH2 has been described as playing central role in the immune response in several diseases, like asthma and idiopathic pulmonary fibrosis. Although STAT6 has been identified as an attractive therapeutic target, developing an inhibitor has been challenging due to the inability of charge inhibitory molecules to traverse the plasma membrane. The company‘s novel molecule is delivered is a pro-drug that is converted to an active form within the cytoplasm then proceeds to bind to the STAT6 molecule and prevent signal transductio

Extent of SBIR involvement

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Synopsis: Awardee Business Condition

Employee Range
Revenue Range
Less than .5M
VC funded?
Privately Held
Stock Info
IP Holdings

Awards Distribution by Agency

Most Recent SBIR Projects

Key People / Management

  Atul Varadhachary -- President

  Dev Chatterjee -- Director of R&D

  David Brian Corry

  Dipali Date -- Business Development

Company News

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