SBIR-STTR Award

Rapid Self-Decontaminating Textiles
Profile last edited on: 12/14/16

Program
SBIR
Agency
NSF
Total Award Amount
$649,440
Award Phase
2
Principal Investigator
Charles A Howland
Activity Indicator

Company Information

Warwick Mills Inc

301 Turnpike Road PO Box 409
New Ipswich, NH 03071
   (603) 291-1000
   inquiries@warwickmills.com
   www.warwickmills.com
Multiple Locations:   
Congressional District:   02
County:   Hillsborough

Phase I

Phase I year
2010
Phase I Amount
$149,960
This Small Business Innovation Research (SBIR) Phase I project proposes to develop advanced antiseptic textiles to be used in garments to prevent cross contamination of antibiotic-resistant pathogens. Drug-resistant pathogens Methicillin-resistant Staphylococcus aureus (MRSA), Vancomycin-resistant Staphylococcus aureus (VRSA), and Clostridium difficile represent a significant public health problem. The goal of the project is to develop a textile system to provide active biocidal activity on both the outside and skin-side of the garment. Prevention of cross contamination requires 3-log pathogen kill in 30-90 seconds on a garment?s outside while destruction on the skin-side need not be so aggressive. While existing decontaminating textiles offer 3-log pathogen destruction, their kill times are slow, ranging from 1 hour to 24 hours. While these technologies are useful, they are not effective for cross-contamination control. Personnel from hospitals, transport security, police, and corrections move from one subject to the next in intervals on the order of 30-90 seconds. A novel textile coating system is proposed that can be used in garments to provide these high rates of quick antiseptic performance in less than 90 seconds. The broader impact/commercial potential of this project is to produce rapid self-decontaminating garments to be used by personnel in law enforcement, corrections, TSA transport screening, hospitals and long-term care facilities. In February 10, 2010, Reuters reported that the estimated cost of infections acquired at hospitals alone is $8.1 billion based on a study published in the Archives of Internal Medicine. An initial commercial launch would focus on glove solutions that address hand-hygiene concerns. Gloves would be followed by other garments that require self-decontaminating textiles. Uniforms, lab coats, masks and coveralls offer significant commercial opportunities. Total potential US early adopter headcount is estimated at 900,000 users. The societal impact of this innovation would be to make a significant contribution to infectious disease control, and help prevent transmission of MRSA, VRSA and C. difficile. Not all surfaces can be easily decontaminated, and a successful completion of this SBIR effort would enhance the current scientific and technological understanding of methods to kill drug-resistant pathogens

Phase II

Phase II year
2012 (last award dollars: 2012)
Phase II Amount
$499,480
This Small Business Innovation Research (SBIR) Phase II project proposes to develop a stretchy, disposable, textile glove intended to prevent cross-contamination with 3-log reduction against bio-pathogens in under 90 seconds. Its chlorine coating lasts for three days and unlike nitrile, latex, and vinyl gloves, is breathable, reducing dermatitis associated with continual barrier glove use. Currently antiseptic test standards for textiles, hand wash and hand rubs, AATCC TM-100, BS EN 1499 and EN 1500 are inadequate to accurately evaluate project's goal of 3-log reduction in 30-90 seconds. We developed a new protocol appropriate to these faster times and that specifically measures contact transfer - the Contact Transfer Test Protocol - that measures cross-contaminating efficacy in seconds. This new protocol can be used in the evaluation of other biocidal systems aiming for short pathogen kill speeds. The broader impact/commercial potential of this project, if successful, is an innovation in the field of cross-contamination control. While other attempts to make a self-decontaminating fabric have been made, their 3-log kill times are much longer than the 30-90 second goal of the BioTecT Glove. The new BioTecT Glove represents a significant contribution to the field of pathogen control, such as Vancomycin-resistant Staphylococcus Aureus (VRSA) and Methicillin-resistant staphylococcus Aureus (MRSA) that persist even where strong hand antiseptic and barrier glove programs are in place. While the largest demand for the introduction of an innovative solution intended to decrease the number of facility acquired infections (FAIs) may be in the healthcare field, many other markets such as hospitality facilities, the janitorial field, and correctional institutions can also benefit greatly from this technology. From a financial perspective, the cost of an infectious outbreak to a healthcare facility can be catastrophic. Moreover, the socio-political consequences and the impact on a facility's reputation can create long-term negative impressions that may remain in the public's conscience for extended periods of time. As a rapid, self-decontaminating garment, the BioTecT Glove provides an active, innovative solution to this common and serious problem in an affordable, easy-to-use, and effective manner.