SBIR-STTR Award

Vectors and Methods for Marker Free Transgenic Plants
Award last edited on: 5/21/02

Sponsored Program
SBIR
Awarding Agency
NIH : NIGMS
Total Award Amount
$100,000
Award Phase
1
Solicitation Topic Code
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Principal Investigator
Jane Aldrich

Company Information

Lakeside Biotechnology Inc

814 Sheridan Road
Wilmette, IL 60091
   (847) 251-6161
   N/A
   N/A
Location: Single
Congr. District: 09
County: Cook

Phase I

Contract Number: 1R43GM052256-01
Start Date: 00/00/00    Completed: 00/00/00
Phase I year
1995
Phase I Amount
$100,000
We will develop an optimized transformation system with Agrobacterium to provide marker-free transgene plants. Genetically engineered plants that lack antibiotic or herbicide resistance genes are free of concerns about health and environmental effects that might arise from the use of these marker genes. Moreover, with each new transgene added, a new selectable marker must be used. This proposal will allow development of transgenic plants lacking marker genes and other vector sequences. The marker and transgene contained on two different T-DNAs, each in a different Agrobacterium strain, are introduced into the cell in a process that selects for a co- transformation event. Segregation in the progeny results in recovery of marker-free transgenic plants. Technology obtained in Phase I using Arabidopsis will be transferred to crop plants in Phase II.National Institute of General Medical Sciences (NIGMS)

Phase II

Contract Number: ----------
Start Date: 00/00/00    Completed: 00/00/00
Phase II year
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Phase II Amount
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