SBIR-STTR Award

Immediate Application Cranioplasty During Decompressive Craniectomy for Head Injuries
Award last edited on: 7/10/2014

Sponsored Program
SBIR
Awarding Agency
DOD : DHA
Total Award Amount
$149,556
Award Phase
1
Solicitation Topic Code
DHP13-012
Principal Investigator
Robert C Chin

Company Information

Fabrico Technology Inc (AKA: Gene Xpress Informatics)

13091 Pond Springs Road
Austin, TX 78729
   (512) 219-8588
   N/A
   www.fabricotech.com
Location: Single
Congr. District: 31
County: Williamson

Phase I

Contract Number: ----------
Start Date: ----    Completed: ----
Phase I year
2014
Phase I Amount
$149,556
Fabrico Technology, Professor Leonid Bunegin, and Dr Jeremy W. Canon of the University of Texas Health Science Center at San Antonio (UTHSC-SA), proposes to develop an Electrophoretic Decellularization Chamber (EDC) technology to produce a rigidity tuned Electrophoretic Decellularized Bio-Scaffold (EDBS) Cranial Bone - ExtraCellular Matrix (CB-ECM) Cranioplasty Prototype Construct (CPC) for the eventual use and sale to 3rd-party scientists and companies for cranioplasty applications. The EDBS CB-ECM will be generated using Fabrico?s EDC technology to efficiently decellularize cranial bone of various shape and rigidly characteristics. To design and demonstrate the operation and functionality of the CB-ECM CPC applications, Fabrico proposes to develop a high fidelity Cranioplasty simulator. The simulator is based upon innovative material, which is easily moldable, inexpensive and capable of mimicking the mechanical properties of brain, Dura, arteries, and skin. The realistic brain model will be designed to demonstrate the viability of the CB-ECM CPC implant that is semi-rigid and capable of conforming and adapting to expansion of the brain during simulated and actual brain edema. Deliverables will include a device development and testing plan for phase II and research protocols for animal and human testing for final CPC use in Forward Surgical Team and Combat Support Hospital.

Keywords:
Extracellular Matrix, Tbi, Electrophoresis Decellularization, Cranioplasty, Cranial Bone, Brain Simulator

Phase II

Contract Number: ----------
Start Date: ----    Completed: ----
Phase II year
----
Phase II Amount
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