Infectious Disease Diagnostics and Differentiation of Viral vs. Bacterial Infections for Point ofCare Applications
Award last edited on: 5/16/2023

Sponsored Program
Awarding Agency
Total Award Amount
Award Phase
Solicitation Topic Code
Principal Investigator
Paula Koelle

Company Information

Genecapture Inc

601 Genome Way
Huntsville, AL 35806
   (256) 783-4506

Research Institution

University of Texas

Phase I

Contract Number: HDTRA1-16-C-0051
Start Date: 00/00/00    Completed: 00/00/00
Phase I year
Phase I Amount
The modern warfighter faces the constant threat of endemic infections, multi-drug resistant bacteria and Biological Warfare Agents. In order to provide accurate front-line treatment that will curtail the overuse of antibiotics, a rapid and robust molecula

Phase II

Contract Number: HDTRA1-18-C-0031
Start Date: 00/00/00    Completed: 00/00/00
Phase II year
(last award dollars: 2021)
Phase II Amount

GeneCapture, Inc. is proposing to develop a rapid in vitro diagnostic prototype using our patented molecular-based CAPTURE (ConfirmActive Pathogens Through Unamplified RNA Expression) assay. Based on the results and experience gained in our Phase I STTR contractHDTRA1-16C-0061: Infectious Disease Diagnostics and Differentiation of Viral vs. Bacterial Infections for Point of Care Applications, we plan tocontinue our device maturation by integrating automated sample preparation into the disposable cartridge, modifying the fluid path foroptimal target acquisition, expanding the Febrile Illness panel and progressing the commercialization of the product. The goal of this Topic is aportable pathogen detection system for undifferentiated febrile illnesses for use in far-forward environments by the Warfighter. Thepathogens of interest for this Phase II effort include Influenza, Dengue, Chikungunya, Lassa Fever, and Crimean-Congo Hemorrhagic Feverviruses, and the bacteria Yersinia pestis, Rickettsia typhi, Francisella tularensis and Burkholderia species. The assay will also differentiatesamples containing bacterial agents from those containing fungal or viral pathogens.