SBIR-STTR Award

Novel Protein Nanodelivery Systems for Biological Agent Countermeasures
Profile last edited on: 3/25/08

Program
SBIR
Agency
Army
Total Award Amount
$849,804
Award Phase
2
Principal Investigator
Ray Yin
Activity Indicator

Company Information

ANP Technologies Inc

824 Interchange Boulevard
Newark, DE 19711
   (302) 283-1730
   info@anptinc.com
   www.anptinc.com
Multiple Locations:   
Congressional District:   00
County:   New Castle

Phase I

Phase I year
2005
Phase I Amount
$119,960
We propose to develop a universal strategy to encapsulate protein-based therapeutics using our patented non-toxic, non-immunogenic, water soluble, nanometer size capsules. These nanocapsules have a functionalized surface rendering them "unseen" by the normal immunogenic scavenging response of the body. In addition, the nanoencapsulated proteins not only exhibit superior shelf stability, but are also capable of withstanding various (harsh) formulation conditions without loss of protein activity

Phase II

Phase II year
2005 (last award dollars: 2005)
Phase II Amount
$729,844
We propose to continue the development and characterization of a polymeric nanoencapsulation technology that can increase the lifetime of a protein therapeutic agent within a biological system. The materials have been demonstrated to exhibit no cytotoxicity and to efficiently deliver antibody against Protective Antigen of bacillus anthracis.

Keywords:
NANOENCAPSULATION, NANOMATERIALS, THERAPEUTIC, ANTI-PA