In December of 2004, Micro-Probe Corporation (Epoch Bioscience) was acquired by Nanogen, Inc. (Nasdaq: NGEN), another SBIR firm. Originally known as Micro-Probe Corporation also (Microprobe), in 1998 firm name changed to Saigene. From that point, having sold most of its diagnostics business to Becton-Dickinson & Co, all SBIR awards were made to the firm Epoch Pharmaceuticals which then was recently renamed Epoch Bioscience (NASDAQ).