Acpharis Inc. provides routine and innovative applications of computational methods to the biomedical problems investigated by its partners. Essentially target the right proteins with the right molecules, the firm's computational solvent mapping - determine which proteins are druggable, their binding sites, and when it is necessary to move beyond Rule of Five molecules into the frontiers of macrocycles and foldamers - dentifies druggable binding sites and classifies what type of molecules they will bind.The firm's activities include homology modeling of proteins, high throughput virtual screening of databases, and the assessment of compounds in libraries selected by the company's partners; and innovative activities involve the development and use of non-standard drug design technologies and computer programs. The company explores the druggability of target proteins selected by its partners; identifies and characterizes druggable binding sites; and selects functional groups to be used for the design of targeted compound libraries.
