SBIR-STTR Award

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Conformable Osteochondral Repair Platforms for Prevention of Post Traumatic Osteoarthritis
Award last edited on: 9/28/2020

Sponsored Program
SBIR
Awarding Agency
DOD : DHA
Total Award Amount
$1,299,030
Award Phase
2
Solicitation Topic Code
DHA17-009
Principal Investigator
George Klarmann

Company Information

Theradaptive Inc

539 Metropolitan Court
Frederick, MD 21704
   (617) 454-4050
   info@theradaptive.com
   www.theradaptive.com
Location: Single
Congr. District: 06
County: Frederick

Phase I

Contract Number: W81XWH-17-C-0128
Start Date: 7/19/2017    Completed: 2/18/2018
Phase I year
2017
Phase I Amount
$149,999
Our proposal develops an osteochondral repair platform that is conformable to a wide variety of injury geometries without the need for pre-operative customization. Further this platform does not rely on any autologous tissue and is amenable to scalable manufacturing methods. The basis of this platform is a targeted delivery technology that permits site-specific osteo-chondral induction within injury sites. The biologic carrier platform is able to deliver multiple osteoinductive and chondro-inductive biologics in a spatially controlled way that permits cartilage repair that is distal to bone repair. This allows the surgeon to mold the implant to any geometry and to control where bone and cartilage repair occur in a seamless manner that mimics natural articular cartilage integration into supporting bone.

Phase II

Contract Number: W81XWH18C0325
Start Date: 6/15/2020    Completed: 10/20/2022
Phase II year
2018
Phase II Amount
$1,149,031
Our proposal develops an osteochondral repair platform that is conformable to a wide variety of injury geometries without the need for preoperative customization. Further this platform does not rely on any autologous tissue and is amenable to scalable manufacturing methods. The basis of this platform is a targeted delivery technology that permits site-specific osteo-chondral induction within injury sites. The biologic carrier platform is able to deliver multiple osteoinductive and chondro-inductive biologics in a spatially controlled way that permits cartilage repair that is distal to bone repair. This allows the surgeon to mold the implant to any geometry and to control where bone and cartilage repair occur in a seamless manner that mimics natural articular cartilage integration into supporting bone.