SBIR-STTR Award

Neuromonitoring of Traumatic Brain/blast Injury
Award last edited on: 1/5/2022

Sponsored Program
SBIR
Awarding Agency
DOD : Army
Total Award Amount
$849,967
Award Phase
2
Solicitation Topic Code
OSD09-H06
Principal Investigator
Dave Popovich

Company Information

Advanced Brain Monitoring Inc (AKA: ABM~B-Alert)

2237 Faraday Avenue Suite 100
Carlsbad, CA 92008
   (760) 720-0099
   N/A
   www.b-alert.com
Location: Multiple
Congr. District: 49
County: San Diego

Phase I

Contract Number: ----------
Start Date: ----    Completed: ----
Phase I year
2010
Phase I Amount
$99,973
It is well known that the brain is the organ most sensitive to ischemia/hypoxia. Noninvasive continuous monitoring of cerebral blood flow autoregulation, cerebrovascular reactivity and related phenomena such as cerebral vasospams in combat casualties could guide clinicians/medics in adjusting the strategy of resuscitation and acute care, and therefore contribute to a substantially improved survival and functional outcome. We propose to develop a small, light-weight, battery powered and hand-portable 3-channel monitor that combines electro- and rheoencephalography (EEG and REG). While REG detects changes in cerebral vascular bed, EEG can be used to detect post-traumatic non-convulsive seizures or reversible breakdown of the synaptic transmission. The monitor consists of a smaller (2 x 2 x 0.5 in) wearable unit for data acquisition and a larger (7 x 5 x 0.8) unit for visualization and storage of data. The units communicate to each other wirelessly, via a Bluetooth link, or through a cable. The larger unit processes the incoming data in real time, and warns clinicians (via an audio alarm) of a deterioration of the patient''s condition. The bigger unit can connect to a LAN or the internet so that the REG/EEG data can be downloaded and analyzed offline by clinicians.

Keywords:
Noninvasive Monitoring, Electroencephalography (Eeg), Rheoencephalography (Reg), Cerebrovascular Reactivity, Cerebral Blood Flow Autoregulation, Combat Casualties

Phase II

Contract Number: ----------
Start Date: ----    Completed: ----
Phase II year
2011
Phase II Amount
$749,994
It is well known that the brain is the organ most sensitive to ischemia/hypoxia. Noninvasive continuous monitoring of cerebral blood flow autoregulation, cerebrovascular reactivity and related phenomena such as cerebral vasospams in combat casualties could guide clinicians/medics in adjusting the strategy of resuscitation and acute care, and therefore contribute to a substantially improved survival and functional outcome. In Phase I we developed a small (3.5 x 2.5 x 0.7 in), light-weight (<4oz), battery powered and hand-portable 3-channel monitor that combines electro- and rheoencephalography (EEG and REG). While REG detects changes in cerebral vascular bed, EEG can be used to detect post-traumatic non-convulsive seizures or reversible breakdown of the synaptic transmission. The monitor can transfer the data in real time via either a Bluetooth link or standard USB connection. The monitor also has sufficient memory to store the raw data from > 300 hours of recording.

Keywords:
Tramatic Brain Injury, Reg, Eeg, Cerebral Blood Flow Auto Regulation, Hemorage, Resuscitation