Digestive wellness

Broad Areas of Interest	12
Specific areas of technology interest	25
About White Papers (WP): Key to invite decision is perceived relevance of SBIR awardee skills sets and capabilities to P&G Healthcare interests. White Papers are your way of setting out your store. What is a White Paper?     Some listed Topics here are quite narrowly specific; others more open-ended. To that end, TWO types of White Paper are assumed. Topic specific: You have technology and/or capabilities relevant to a specific topic (or two-three related topics). Using WP Template in your Private Work space, you take that narrow focus. Addressing more than ONE related Topic, simply cite those in prepared piece rather than offer multiple versions of same. ...more General overview: P&G having opted to assume a longer term focus (5-7-10 years), by definition there is overlap between several of the working topic ideas and many assume some need to be further back in the development cycle. Where this would be the basis of your innovation@work discussion, your White paper(s) may well be more broadly scoped. These papers should be submitted to the First Listed Topic - Context setting, cross-project enabling capabilities. ...more Reviewers: Each division of P&G will, in major part, review WP submitted only to their own topics. Cross-reference pre-event of your discussed capabilities to other divisions cannot be assumed. If your expertise crosses business boundaries, therefore, submit relevant White Papers for consideration by each set of reviewers. ...more

Gastrointestinal symptoms are among the leading causes of morbidity in both the developed and developing world. Given the importance of this area, for more than two decades, P&G Health Science Institute scientists have explored ways to improve gastrointestinal health.
     That work has already helped develop new treatments for ulcers and traveler's diarrhea; explored the role of bismuth subsalicylate in treating children's diarrhea; explored the role of psyllium, a type of soluble fiber, in lowering blood cholesterol and managing diabetes and irritable bowel syndrome; and, demonstration that a new class of powerful medications, proton pump inhibitors, can be used safely and effectively to treat frequent heartburn symptoms in OTC use. Frequent heartburn affects more than 40 million Americans and this promising research is poised to make a dramatic intervention to improve people's lives.
     As part of this process, P&G personnel have collaborated with some of the world's top thought leaders regarding emerging scientific discoveries that could make their way into products providing new digestive health solutions. Indicative of that discovery approach, the following short list describe the broad topic areas of interest.    
     P&G are interested in hearing from - and potentially meeting with in November - SBIR awardees with capabilities and ideas relevant to any one (or more) of these areas. Think of these are being much like the NIH areas of interest seeking investigator initiated work.

Broad Areas of Interest		Number of Broad Topics to date: 12
Check topics of interest. Add to My Work Area button at bottom of listing will move these to your on-site office for attention at your convenience.
Topic Title		Indicators of interest levels
		Firms Interested	White Papers Submitted	Questions Asked
Context setting, cross-project enabling capabilities (DW)		5	1	0
Treatment of digestive symptoms		2	1	0
Digestive symptoms		0	0	0
Identification of digestive conditions		1	0	0
Digestive Therapies		0	0	0
Treatment of digestive disorders		1	1	0
Non-invasive digestive diagnostic methods		2	1	0
Science, methodologies, analytical methods and treatments related to upper and lower GI tract, digestive enzymes and gastric function		0	0	0
Technology-based targeted fiber delivery systems		0	0	0
Technology inhibiting the growth of pathogenic bacteria throughout the GI tract		1	0	0
Novel dose forms		1	0	0
Non-invasive methods to detect and/or diagnose any of the following: Gas; Indigestion; Food allergies; Heartburn; Over-indulgence; Flatulence; or Bloating.		2	0	0

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Technology Areas of Interest Developed by P&G personnel, the Topics listed below are somewhat more narrowly focused with in most (but not all cases) some useful indicators of what the listing source is looking for in terms of benefits sought, new actives, delivery methods etc.			Number of Topics to date: 25
Check topics of interest. Add to My Work Area button at bottom of listing will move these to your on-site office for attention at your convenience.
Topic Title		Description	Indicators of interest levels
			Firms Interested	White Papers Submitted	Questions Asked
Methods of directly or indirectly enhancing the function of the gut and systemic immune system			3	1	0
Methods of preventing or treating upper/lower gastrointestinal health issues (IBS, gas, bloating, etc)			2	0	0
Technologies that help control the proliferation of “bad” bacteria			1	0	0
Technologies that offer anti-inflammatory properties			2	0	0
Methods of sustaining the balance of potentially harmful and helpful bacteria in the microflora of the colon			2	1	1
Technologies that enhance the adherence of materials to mucosal tissues to drive various benefits including heartburn and cough			1	0	0
Technologies that reduce the symptoms specifically related to overeating and/or overindulgence i.e. fullness, bloating and/or gas		NOTE: this topic is more specifically related t... ...more	1	0	0
Methods to identify the specific health benefits of prebiotics, probiotics, fibers and synergistic formulas or combinations of these			1	0	0
Methods for measuring vitamin/mineral/nutrient levels in the body and their effects			2	0	0
Methods (non-invasive) for detecting and/or diagnosing GI conditions e.g., lactose intolerance, gluten allergy, acid reflux			2	0	0
Methods (non-invasive) for detecting signs of health/wellness			2	0	0
Understanding the mechanism of action of indigestion - non-ulcer dyspepsia		Benefits sought: Technology en... ...more	1	0	0
Understanding vitamin and mineral adsorption		Benefits sought: Enhanced prob... ...more	2	1	0
Probiotic survivability (glass transition, temperature, etc)		Benefits: Reduce/prevent small bowel over-growth New ... ...more	1	0	0
Protection of Probiotic cryoprotectant, enteric coating, resist gastric acid, humidity and temperature tolerant		New actives: Technologies to relieve fullness Deliver... ...more	2	0	0
Gel characterization of edible fibers		New actives: carbohydrases	0	0	0
Health benefits of Probiotics beyond digestive wellness; Mechanism of Action of Probiotics		New actives: Fiber with gelling properties that can deliver ... ...more	0	0	0
Sensory measurements (i.e., objective measurements of pain/discomfort)		New actives: Pre and Probiotics with digestive wellness bene... ...more	1	0	0
Bloating/Fullness Measurements		New actives: Digestive acid-neutralizing food-safe materials... ...more	1	0	0
Screening methods for fibers and their effectiveness in controlling digestive disorders			1	0	0
Removal of Toxins/contaminants From the Body		Orally-ingested ingredients the remove toxins or contaminant... ...more	1	0	0
Enhancement of Gut Function and Systemic Immune System		Products or ingredients that directly or indirectly enhance ... ...more	1	0	0
Control of "bad bacteria"		Technologies or ingredients that help control the proliferat... ...more	2	0	0
Promote or Maintain Healthy Intestinal Flora		Clinically proven ingredients that help maintain a healthy b... ...more	1	0	0
Complimentary Ingredients to Improve Gastrointestinal Health		Ingredients that can be added to psyllium, inulin, and/or pr... ...more	1	0	0

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