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Public Profile: Acelot is a drug development company applying novel patented searching and mining algorithms to complex biological and chemical data to discover new leads for central nervous system diseases and various types of cancer. Acelot's capability to analyze large biological pathways opens up new and previously unknown options for drug targets. Acelot's unique graph-based in-silico approach results in small molecule leads that are both novel and tailored to biological targets while minimizing the risk of side-effects. Acelot is currently focusing on new leads for Alzheimer's Disease that act on lesser-studied biochemical pathways. Acelot offers a suite of searching and mining tools to allow users to mine their own drug development pipeline. The current suite of tools supports * Screening of large chemical databases and scaffold hopping → SimFinder™ * Discovery of active substructures for lead generation and optimization → SigFinder™ * ADMET prediction with structural reasoning → ActiPred™and * Advanced pharmacophore analysis → PharmaMiner™ Acelot's drug discovery tools have been integrated into popular cheminformatics frameworks and are also offered as stand-alone solutions.