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Relevant Dates |
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Interest Indicator: |
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September 16, 2008:
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Nutshell Submission: |
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October 3, 2008:
Final date for approval of Nutshells and receipt of all related Showcase Material.
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| Useful Nutshell content and layout: Examples |
 
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Available Payment Options
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First-time Nutshell Applicable fee |
$295.00
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Payment not required to submit Interest Indicator
Fee of $295.00 will be required before the Nutshell upload Fee refunded in full if your submissions are not accepted.
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Nutshell renewal
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Those who have previously had a Nutshell that has been used on distributed CDs and are renewing or have allowed their Account to lapse may
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Description of
Advanced Individual Account |
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The Advanced Individual account is a useful combination On- and Offline Services system with associated Redeemable Points and continuing Discounts enabling SBIR Awardees serious about achieving in-use condition of their technologies and capabilites to have
full online search access to the multi- element, comprehensive idi SBIR-STTR databases and
full use of the diversity of SBIR consulting, tech transfer and marketing efforts in which this firm engages year round.
All elements of the Nutshell system - to include free updates annually - are integrated into that account along with various other useful collective and individual promotional and informational services.
Well worth your consideration!
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| Featured Company Nutshells |
Total Nutshells: 53 |
| Name of Firm |
City, State |
Company Nutshell |
Business Profile |
| Acumentrics Corporation |
Westwood, MA |
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Durable, reliable, and high-performance power supplies for challenging applications. Breakthrough fuel cell technology integrated into established rugged power conversion and back-up units. This RUPS capable of: • Surviving wide temperature extremes • Tak-ing a beating from water, dust, shock and vibration • Operating from both DC and AC sources, and delivering both AC and DC outputs • Using any frequency or voltage of AC power found anywhere in the world or from any power generating source and converting it to US-quality, pure power for critical telecom and digital equipment. Solid oxide (or ceramic) fuel cells (SOFCs) - fast-starting tubular SOFC developed that avoids most of the problems of ceramic fuel cells by using a tubular shape |
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| APC Biotechnology Services Inc |
Rockville, MD |
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Novel bioprocess platform; recombinant peptides and small proteins; vaccines; custom immunogens; therapeutics. Firm has developed a novel peptide and protein bioprocess platform with which to offer custom recombinant peptide or protein synthesis and bio-process development services. A complete set of custom product development services, product-specific assay development (including ELISA) and analytical testing services are offered for clients with recombinant protein and peptide drugs |
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| Aphios Corporation |
Woburn, MA |
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Specialty pharmaceutical company developing enhanced natural therapeutics for health maintenance, treatment of cancer and infectious diseases. Using Company's library of diverse marine microorganisms isolated from normal to extremeophilic environments in United States territorial waters, developing antiviral and antimicrobial therapeutics. Portfolio includes several anti-HIV, anti-Influenza and anti-Smallpox 'hits,' and a marine antimicrobial compound effective against multi-drug resistant (MDR) human pathogens, methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Entero-coccus faecium (VRE). Proprietary products in: 1) low temperature viral inactivation for blood plasma, animal serum and recombinant therapeutics; 2) natural product manufac-turing for therapeutics such as Taxol and other anticancer agents; 3) liposome formula-tion of chemotherapeutic drugs and recombinant proteins; and 4) selective microbial cell disruption for the recovery of intracellular proteins and periplasmic enzymes. |
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| Applied Systems Intelligence Inc |
Alpharetta, GA |
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Knowledge based software products designed to assure performance when failure is not an option by providing time-critical situational awareness, dynamic planning, and auto-mated activity execution. Early applications include DARPA Pilot's Associate Program to aid F22 pilot. Other military users have included: * US Army's Rotorcraft Pilot's As-sociate * NASA's Advanced Air Transportation Technologies * Joint Unmanned Combat Air System Program * US Army's Future Combat System. Other in-use applications in-clude: Command and Control Operations-Role Based Information Delivery (Land War-fare, Civil First Responder ); Intelligence Analysis; Chemical, Biological, Radiological and Nuclear-Intelligent Sensor Applications; Unmanned Systems Operations; Medical Analytics; Dynamic Business Process Management; Supply Chain Management; Intelli-gent Network Management. |
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| Automated Dynamics |
Schenectady, NY |
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Manufacture advanced composite structures and high performance composite processing equipment. Currently focused to Engineered Composite Structures and Affordable Auto-mation for Composites utilizing proprietary automated fiber placement (AFP) and auto-mated tape laying (ATL) technologies to fit thermoplastic and thermoset application needs. |
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| Beacon Interactive Systems LLC |
Cambridge, MA |
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Integrated Work Management Systems seamlessly blending System Automation with Hu-man Performance data to provide an Open Innovation work platform permitting in-creased efficiency at all levels of the organization. Products enable groups to leverage their knowledge and talent with each other and to blend this with enterprise data to pro-vide a powerful linkage of information, functionality, processes and people. |
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| BetaStem Therapeutics Inc |
San Francisco, CA |
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An early stage R&D firm developing specific cellular therapy for treatment of diabetes, and a patent-pending pancreatic developmental assay that will accelerate the detection of novel, required factors or drugs involved in human beta cell development and regen-eration. Another platform is based on patented procedure to modify adult hematopoietic stem cells (HSC) just prior to transplant - demonstrating that adult stem cells can be transplanted more efficiently for the treatment of cancer and vascular disease and that human embryonic stem cells (huES) can be used as remarkable tools to identify human proteins important in diabetes. |
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| BlueForce LLC |
BlueForce LLC, VA |
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Values-based, in-depth, operational subject matter expertise with emphasis on command and control, expeditionary operations, modeling and simulation, acquisition manage-ment, aerospace operational planning, requirements, information technology systems and processes. Products and services support operational-level command & control, emer-gency management, port security and business intelligence. |
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| CFD Research Corporation |
Huntsville, AL |
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A mature, larger small firm firm, CFD Research Corporation (CFDRC) now offers capa-bilities in two areas - Biomedical and Emerging Energy and Materials Technologies and - Aerospace and Defense Solutios. Two Nutshells. Former includes Microfluidic systems (lab-on-chip);
1. Biochips for Synthetic Microvasculature Networks Biomedical devices; Computa-tional Medicine, Systems Biology, and Bio-Informatics. Work in Emerging Energy & Materials technologies includes biobattery, fuel cells, quantum dot solar cells, (nano-)materials processing and fabrication.
2. Aerospace & Defense Division develops analysis software, hardware prototypes, and provides custom solutions and services for: Aeromechanics (aerodynamics, aero-thermodynamics, aeroelasticity, crew escape); Propulsion (engines, propellants, gels, ignition); Combustion (low emissions gas turbines, fuel injectors); Space Electronics (radiation hardening, solar cells), and Homeland Security (CBRN/E) |
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| CFD Research Corporation |
Huntsville, AL |
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A mature, larger small firm firm, CFD Research Corporation (CFDRC) now offers capa-bilities in two areas - Biomedical and Emerging Energy and Materials Technologies and - Aerospace and Defense Solutios. Two Nutshells. Former includes Microfluidic systems (lab-on-chip);
1. Biochips for Synthetic Microvasculature Networks Biomedical devices; Computa-tional Medicine, Systems Biology, and Bio-Informatics. Work in Emerging Energy & Materials technologies includes biobattery, fuel cells, quantum dot solar cells, (nano-)materials processing and fabrication.
2. Aerospace & Defense Division develops analysis software, hardware prototypes, and provides custom solutions and services for: Aeromechanics (aerodynamics, aero-thermodynamics, aeroelasticity, crew escape); Propulsion (engines, propellants, gels, ignition); Combustion (low emissions gas turbines, fuel injectors); Space Electronics (radiation hardening, solar cells), and Homeland Security (CBRN/E) |
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| Ciencia Inc |
East Hartford, CT |
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Integration of advanced fluorescence sensing instrumentation, novel fluorescent dyes, and proprietary assay methods with sophisticated analytical systems targeted to broad applications in biomedical research, environmental and industrial markets. Enablesg dramatic reduction in the size and cost of instrumentation while achieving commensurate increases in assay sensitivity, speed and robustness. Optical diagnostics instrumentation for biomedical, environmental and process analysis markets: tunable optical filters, holographic filters, fiber-optic based sensors for on-line real-time chemical analysis, hy-perspectral imaging polarimeters for remote sensing, phase fluorometry instrumentation, Raman spectroscopy instrumentation for optical biopsy of tissues, biosensors and a fluo-rescence-based cell analysis system. |
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| Cool Energy Inc |
Boulder, CO |
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Distributed energy system based around a solar thermal Stirling engine for combined heat and power using evacuated tube solar collectors to provide thermal energy to a building, and generating electricity when heating needs are met. Advanced control sys-tem maximizes economic payback by producing the highest-value energy, heat or elec-tricity, demonstrating majorly shortened payback periods with important user advantage of a single energy system addressing space heating, hot water, and electrical power. |
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| Curio Systems Inc |
Oak Hill, VA |
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Automated rare event statistical analysis, surveillance and reporting. A new and innovative approach to analyze rare events in ways not currently served by existing market offerings and without the need for advanced statistical analysis expertise. Potentially powerful tracking applications include: Pharmaceutical companies tracking production errors, clinical trial results, patient side effects, etc. Clean energy companies tracking pollutant emissions, emissions control efforts, etc. Blood and plasma banking organizations tracking donor population rates of infectious disease markers, donor deferrals, etc. Public health organizations conducting biosurveillance of infectious disease outbreak markers, public health risks, etc. Port security officials tracking inspection results of container security inspection reports for contraband shipments, by shipper, shipment type, etc. Hospitals tracking the numbers and types of hospitalacquired infections, such as MRSA, ventilatoracquired pneumonia, etc. |
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| Cybernet Systems Corporation |
Ann Arbor, MI |
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A longestablished, hightech developing facility with expertise and product capabilities in Software Intelligence etcentric Sharing and Security Medical Devices & Systems ManMachine interaction Tactical Automation and Robotics |
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| EIC Laboratories Inc |
Norwood, MA |
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Expertise in lithium and lithium-ion batteries, electrochromics, Raman and other spectroscopic sensors and instruments, electrodes and materials for functional electrical stimulation, chemical sensors and advanced organic materials design and synthesis. |
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| Eltron Research and Development Inc |
Boulder, CO |
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A mature small firm focused to moving to use-condition high quality research undertaken by previous principals in a range of areas to include:
Catalytic Membrane Reactors (CMR’s) * Hydrogen Transport Membrane * Oxygen Transport Membrane* CMR for Oxidative Dehydrogenation of Methane and Ethane to Ethylene* Integrated Water Gas Shift / H2 Transport Membrane* Integrated O2 CMR with Natural Gas Partial Oxidation* Integrated O2 CMR with Liquid Fuel Partial Oxi-dation* Coal Gasification with O2 Catalytic Membrane Reactor
Electrolytic Systems * Hydrogen Peroxide Generator * Electrowinning/ Electrorefining
Catalysis * Low Temperature VOC Destruction * Non-Cobalt Fischer Tropsch Catalyst with Reverse WGS Activity* Natural Gas to Syngas via Chemical Looping Reactor * Nanostructured Metallomacrocycle Carbons for Use as Cathode Electrocatalysts in PEM Fuel Cell * Selective Removal of Carbon Monoxide* Catalyst for Catalytic Wet Air Oxi-dation * Chemical Looping Coal Gasification* Passive Lean-NOx Catalyst * High Tem-perature Heterogeneous Redox Catalyst for NOx Abatement * Catalysts for Low Tem-perature Destruction of Chemical Warfare Agents * Adsorbents for Chemical Agents
Materials * Synthesis of Phosphate Lithium-Ion Cathode Materials * Electron-Conducting Refractory Oxide Coatings * High Voltage Insulating Paint * Aluminum Ni-tride-Oxide Coatings for Hot Pipe Protection* Reverse Osmosis and Nanofiltration Membranes * Polyhedral Oligomeric Silsesquioxane (POSS) Modified Epoxy Resins* Processable Polyimides for Resin Transfer Molding (RTM) Fabrication of Fiber Rein-forced Composites * Incorporation of Single Walled Carbon Nanotubes into Thermoset and Thermoplastic Composites
Sensors * Detection of Hexavalent Chromium in Water * Field Monitor for Chemical Warfare Agents * Comprehensive Oil Quality Sensor * Arsenic Monitor for Water * Real-Time TOC Analysis for Ultra-Pure Water * Dry Cleaning Personal Exposure Moni-tor* Nitrate and Nitrite Detection in Groundwater |
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| Endomedix Inc |
Stony Brook, NY |
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Highly biocompatible, biodegradable, environmentally-responsive, natural hydrogel for multiple medical applications. Similar to fibrin glue containing two stable components at room temperature, core components are not derived from synthetic materials or blood products. Initial cytotoxicity data shows minimal inflammatory reaction. Applications in wound care, tissue sealing, vascular surgery, general surgery, spine surgery, ophthalmic surgery, neurosurgery, and drug delivery. Current preclinical studies focused on (1) wound care showing improved efficacy over silvadene; (2) vascular embolic for the treament of abdominal aortic endoleaks, arteriovenous malformations, and brain aneu-rysms; (3) tissue sealing; (4) hemostatic agents; and (5) spinal applications. |
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| Ferrate Treatment Technologies LLC |
Orlando, FL |
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Water and wastewater treatment technologies. Proprietary iron chemistry platform. ena-bling a synthesis process and a reactor system to manufacture “Ferrate” on site. Ferrate a high-valence form of iron synthesized from Iron Three or Fe (III) up to Iron Six or Fe (VI). Ferrate (Fe6+O4)2- among most powerful, multi-purpose, and yet environmentally friendly treatment compounds known. Commercial use previously limited by seemingly unsolvable problems related to manufacturing costs and product instability. FTT’s inno-vative approach is distinguished from prior synthesis methods: the resulting product is a liquid instead of solid; the product can now be directly injected into a process stream without special handling or mixing equipment; and synthesis can be achieved utilizing existing bulk chemical feedstocks available at most plants. With a new breakthrough class of small, inexpensive, transportable synthesis reactors, Ferrate can now be deliv-ered continuously on-site for chemical, industrial, and environmental treatment proc-esses in commercially significant quantities. |
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| Freight Pipeline Company |
Columbia, MO |
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Innovative, new technologies to include
capsule pipeline for efficient, cost-effective, safe and environmentally-friendly trans-portation of freight,
and the high-pressure compaction area for manufacturing of new products made of biomass, coal ashes, and other solid waste materials.
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| Giner Inc |
Newton, MA |
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Proton-exchange membrane (PEM) based electrochemical technologies applying mem-brane technology to fuel cells for power generation, high-pressure electrolyzers for regen-erative power, hydrogen fuel production, and oxygen production for life support (GES). Electrochemical gas sensor technology and high-pressure, undersea electrolyzer technol-ogy. Electrolyzer technologies for hostile environments, capacitors for space and bio-medical applications; and electrochemical gas concentrators for atmospheric control. Col-laboration between Giner, Inc. and General Motors involves research, development, and services for the next generation of transportation fuel cells systems. Also developed are fuel cells for stationary and portable power; regenerative fuel cells for military long-endurance, high-altitude applications; electrolyzers for nuclear hydrogen production; and high energy military fuel systems. |
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| Global Technology Connection Inc |
Atlanta, GA |
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Predictive Maintenance; Modeling and Simulation; Advanced Materials and Failure Pre-vention/Analysis. Innovative products substantially reduce the maintenance costs, in-crease uptime (availability) and improve safety in a variety of equipment and machinery such as HVAC, Pumps, Batteries, Generators, Power Turbines, Trucks etc. |
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| Housey Pharmaceutical Research Laboratories |
Southfield, MI |
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Leveraging on in-house expertise in the field of cell-based assay technology, by combin-ing it with additional technologies, present concentration is specific forms of human cancer and type II diabetes. Expect to expand into other therapeutic areas including cen-tral nervous system disorders, autoimmune disorders, and infectious disease. |
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| Humanitas Inc |
Silver Spring, MD |
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Automated tools and technology solutions to assist health professionals manage cancer clinical trials overseen by the National Cancer Institutes (NCI) Cancer Therapy Evalua-tion Program (CTEP). Products include ePanel© - a web-based review management system used to facilitate streamlined reviews. Web TIE - a gateway for interactive, web-based applications for health professionals participating in clinical trials. Common Tox-icity Criteria (CTC) for palm devices/PDAs - provides health professionals access to NCI/CTEPs CTC respository for use in adverse drug experience reporting, Adverse Events (AE) summaries, Investigative New Drug (ING) reports to the FDA, and publica-tions. eMobile, a remote data collection and reporting application that operates on a wireless mobile device. |
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| Infoscitex Corporation |
Waltham, MA |
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With emphasis on advanced materials technologies and systems engineering, products currently under development include prosthetic spinal disc, single stage immunoassayintegrated microfluidic device, battlefieldready needlefree delivery system to protect against organophosphorousbased nerve gases, implantable artificial lung, microrobotic prototype for neurosurgery, 6) urinary drainage catheter stent lock mechanism, low VOC sealants, biosynthesis of energetic materials and their precursors, home care “Active Bottle” for dysphagic infants, electroactive polymer based strategically tuned absolutely resilient structures, wastetoenergy conversion processing system, selfenergized casualty patient warming device, radiationhardened solar cell windows |
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| Innovative Surface Technologies Inc |
Saint Paul, MN |
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Based primarily on new latent-reactive reagents for covalent bonding under gentle, manufacturing friendly reaction conditions, of biomolecules, polymers, and micro/ nano-particles with other surfaces and with one another. Thin-film surface modifications are being developed and demonstrated for improved wet ability, wet lubricity, biomolecule immobilization and super- hydrophobic surfaces. Examples: -
Nanotextured superhydrophobic coatings
Ultrathin (monolayer) coatings for diagnostic microspheres
Biomolecule immobilization for antimicrobial applications
Lubricious coatings
Proprietary photoactivatible crosslinking reagents
Nanofibrillar surfaces for cell culture and tissue engineering
Custom designed coatings for specialty applications |
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| Invocon Inc |
Conroe, TX |
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Precision instrumentation and communication solutions for demanding applications in extreme environments. Sensing and acquisition industries focus: wireless networking technology. With relevant experience in space, aeronautical, missile targets, health & usage monitoring systems (HUMS), medical, non-lethal weapons, structural monitoring, and smart sensors, seventeen unique Invocon systems have flown on 25 Shuttle flights over the past 12 years. Invocon systems part of all future Shuttle flights and validation of ISS module additions, including Wing Leading Edge Impact Detection System – NASA response to 2003 Columbia disaster. Work also on Mis-sile Defense and Troop Condition Monitoring |
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| JDC Phosphate |
Richland, WA |
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Focused on Cost Effective, Phosphate Fertilizer production process. Pilot plant: Green Technology for phosphate production with the “Improved Hard Process” (IHP). Novel improvements to use continuous kiln approach to phosphoric acid production. Reduced environmental footprint of both phosphate mine and production plant; improved logistics and opportunities for regionalization; advances world food production by cutting fertil-izer costs and increasing phosphate yield and crop uptake utilization |
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| Kionix Inc |
Ithaca, NY |
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MicroElectroMechanical Systems (MEMS) technology . Design and fabrication of high-performance, silicon-micromachined MEMS inertial sensors. Company pioneered high aspect-ratio, silicon micromachining based on research originally conducted at Cornell University. Reputation for excellence in MEMS product design, process engineering, and manufacturing. Applies best practices of the IC semiconductor business and uses indus-try-standard fabrication equipment and techniques to construct three-dimensional, mov-ing, silicon structures on the scale of modern microelectronics. Utilizes a deep-silicon, next-generation, proprietary MEMS technology known as plasma micromachining for its high-volume production - enabling production of MEMS products unmatched in per-formance and manufacturing cost. Product innovations inertial sensors, microfluidic sys-tems, microrelays, and micromirror arrays. In collaboration with major corporations, responding to existing product applications and creating new product opportunities in industries as diverse as automotive, consumer electronics, biotechnology, wireless com-munications, and pharmaceutical research. |
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| Knowledge Based Systems Inc |
College Station, TX |
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Analysis, modeling and systems software development company. Completed projects in artificial intelligence and expert systems, geometric reasoning, computer-aided design and manufacturing, manufacturing systems design and analysis, enterprise integration, process modeling, computer-aided software development, systems simulation, business process design and development, and total quality management. |
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| Lynntech Inc |
College Station, TX |
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A long-time involved, substantial player in the SBIR-STTR space with demonstrated ex-pertise in
Alternative Energy (fuel cells, hydrogen production, plasma reforming)
Biotechnology and Health (therapeutics, diagnostics, sensors, disinfection, decon-tamination, drug delivery)
Chemical Synthesis (ozone, chlorine dioxide, hydrogen peroxide, ferrate, diper-oxyacids)
Environmental (soil, drinking water, indoor air, vehicle and industrial
emissions)
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| Med Graph Inc |
Rochester, NY |
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Initially focused to glucose monitoring device market for automatic realtime monitoring of diabetics, firm offers Telemedicine Informatics capabilities to provide medical industry monitoring infrastructure and technology solutions including home healthcare monitoring devices, healthcare delivery professionals, medical research facilities and monitoring support services to diabetic patients.
Improvements over automatic passive collection, transmission and visual display of critical homecare monitoring variables such as glucose, blood pressure, pulse, cholesterol, spirometer and other types of medical diagnostic information. |
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| MicroStrain Inc |
Willston, VT |
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Sophisticated sensor technology with application in medical instruments, health monitor-ing of civil structures (bridges, dams, buildings) and aerospace sensing. Innovative, smart, wireless, microminiature displacement, orientation, and force sensors. Tiny sen-sors in a wide range of applications: knee implants, civil structures, advanced manufac-turing, unmanned military vehicles, and automobile engines. Early focused on micro-displacement sensors for strain measurement in biomechanics research applications. First sensors used in arthroscopic implantation on human knee ligaments. Now aero-space and automotive industry utilize in many groundbreaking projects.
Wireless capability: low power, miniature digital sensors with ready communication to personal computers. Inclinometer product line initially developed to measure angles of limbs for paralyzed limb re-animate, tiny, lightweight gyro-enhanced orientation mod-ules now usedin navigation and control of unmanned systems in military and exploratory robotics applications. Patented temperature compensated differential variable reluctance transducers (DVRT®). Extremely small size, high accuracy and ability to withstand high temperatures, temperature gradients, saline and pressurized oil environments. |
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| NanoScale Corporation |
Manhattan, KS |
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Grounded in anocrystalline metal oxides (anoActive materials) and technologies originally developed at Kansas State University, firm can now accommodate production from small research samples to largescale production of specialized chemicals. In place products include FASTACT: a chemical containment and neutralization system that allows first responders to immediately mitigate toxic chemical releases, including industrial chemicals and chemical warfare agents. anoActive Chemicals: High performance metal oxides that possess unique and uncommon characteristics effective against a wide range of harmful or deadly chemical substances and hazardous compounds, odors, environmental pollutants, toxins, bacteria, viruses, and fungi. anoZorb: a remarkable odor destroying product for use by morgues and funeral homes that is effective against odors commonly associated with decomposition. ChemKlenz: a multiphased safety program that provides facilities and institutions unparalleled immediate response capabilities against unexpected chemical spills and releases. OdorKlenz: the next generation of products and services for the elimination of challenging odors caused by tobacco smoke, spoiled foods, pets, flooding, decay, cleaning products, and industrial chemicals, as well as other noxious odors |
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| NAVSYS Corporation |
Colorado Springs, CO |
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Technological expertise in "GPS innovations" the use of advanced technology and novel system architectures to improve on conventional GPS equipment and methods for specific market applications. High quality technical products and services in GPS hardware design, systems engineering, systems analysis, and software design space. Offer services in three primary areas: Global Positioning Systems, Inertial avigation Systems, and Communication Systems. |
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| Peregrine Power LLC |
Wilsonville, OR |
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Power electronics company focused particularly to products using silicon carbide power semiconductors. Recent projects have included: light-weight power converters for mobile power high frequency converters for all-electric ships variable speed helicopter rotors thermal electric devices wave energy systems variable speed wind turbines.
Firm has special expertise in advanced high temperature packaging for silicon carbide devices. |
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| Physical Optics Corporation |
Torrance, CA |
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Perhaps the leading SBIR-involved firm in terms of number of awards and extent of post-program impact. Systems integrator with expertise in Light Shaping Displays, Informa-tion Technology, Photonic Systems, Electrooptics and Holography.
POC products and technology already at work in consumer appliances, automo-tive displays, machine vision systems, instrumentation such as microscopes, elevators, barcode scanners, projection displays and medical and biomedical systems.
Spin-off companies have made significant contributions in digital fiber optic communication, optical sensing and instrumentation, optical authentication and millime-ter wave technology
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| Physical Sciences Inc |
Andover, MA |
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A longtime established R&D firm with capabilities in
* Chem-Bio Remote Sensing * CBN Sensor Architectures *Terahertz Sensors * Remote Gas Detection * Industrial Process Sensors * Harsh Environment Sensors * Fuel Contamination Monitor * Solid State Dye Lasers * Solid State High Power Lasers * Laser Display Technology * Nonlinear Optical Materials * Laser System Diagnostics * High Temperature Materials * Space Technologies * Advanced Power Sources * Ophthalmic Monitoring |
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| Pragati Synergetic Research Inc |
Cupertino, CA |
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Innovative software solutions for analysis of complex information systems to facilitate re-use, interoperability, and quality assurance. Flagship product: integrated suite of modules presenting cognitively useful perspectives of software systems such as, expert systems, knowledge-bases, databases, and stylized natural-language text. Unique clustering- based technology finds "collaboration groups - sets of terms sharing same operational context, detects partial or fuzzy relationships between terms that exist within or across systems, re-veals potential mapping regions across concept sets beyond those exposed by using sub-string matching and stemming, extracts recurring usage patterns that can serve as useful shortcuts for rapid reuse and componentization and discovers easily overlooked infelici-tous knowledge entry patterns and incompletely specified knowledge. Four functional modules: Query & Search, Mapping, Reuse and Information Extraction. |
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| Precision Combustion Inc |
North Haven, CT |
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With a concentration to energy and chemicals sectors, the firm offers a series of catalytic reactor system breakthroughs supporting product advantage for internal combustion and gas turbine engines, for fuel processing, for air emissions and VOC control, and for oil production. |
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| QED Services Inc |
Gibraltar, MI |
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Fluid power technologies related to energy generation, conservation, and transmittal. Contract in place to develop a passive hydropneumatic suspension system to prevent rollover of HMMWVs. The suspension system can provide other significant safety, fuel economy, and handling benefits on a variety of vehicles, from Formula racers to railway rolling stock. Expressed interest in the concept vary widely, ranging from reduced wheel damage for low profile tires to uniform suspension response for vehicles having significantly different weights when fully loaded or when empty, such as commercial trucks. The new suspension system improves fuel economy by reducing rolling resistance and aerodynamic drag, and by scavenging power otherwise lost as heat in the dampers and unwanted vertical motion of the vehicle. |
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| Radiation Monitoring Devices Inc |
Watertown, MA |
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Grounded in high performance nuclear, optical, xray and magnetic sensors and systems, products and innovations span the fields of science, medicine and industry. Core technologyis the CdTe detector which remains a significant part of commercial operations. Developed to commercial condition have been The Inspector® Lead Paint Analyzer, which employs a small CdTe detector to quickly make onsite determinations. Similarly based on CdTe, firm is an OEM supplier of a surgical probe system, The avigator®, to help physicians locate radio labeled cancerous tissue during surgery.
Current research activities in several programs are focused on semiconductor detector materials, scintillator screens, Si avalanche photodiodes (APDs) and nuclear instrumentation. Responding to the medical imaging community's desire for more versatile, all solid-state designs, we are working on both semiconductor and scintillator solutions for future generations of digital radiographic systems |
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| Rheonix |
Ithaca, NY |
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Spun out of a MEMS product company, and having experienced burden of silicon and glassed based MEMS fluidic systems, focus has been on creation of a new system free of such limitations. Result: an entirely different microfluidic system. First to perform all fundamental functions of a molecular biology lab - sample preparation, purification, am-plification and analysis - in one hand’s-off integrated system. Joint venture in China to enter first clinical trial for Point-of-Care diagnostic system. |
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| Scout Diagnostics LLC |
Louisville, KY |
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New diagnostic tool enabling very early determination of Alzheimer. New tool initially allow testing efficacy of new treatments; eventually will enable early diagnosis, providing option to begin early-stage treatment treatments can be the most beneficial. Effort grounded in discovery of aberrant protein complex found in post mortem and living sub-jects that either have or are in the process of becoming diagnosed with mild cognitive impairment, early stage Alzheimer's Disease (AD) or late stage AD. In the field of Alz-heimer’s disease (AD) research, three observations have received the greatest attention; the appearance of amyloid plaques, the appearance of neurofibrillary tangles, and the presence of neuroinflammation (inflammatory response). The holy grail of AD research has been the search for a single unifying event that would lead to all three hallmarks of the disease. Scout Diagnostics now possesses data that the protein complex is the event. Research shows that know protein complex (biomarker) produces paired helical fila-ments (PHFs) in cell culture - precursor of neurofibrillary tangles; protein complex causes increased production of the beta amyloid peptide in cell culture and the beta amy-loid peptide increases production of the protein complex in choroid plexus cells; results indicate that protein complex activates inflammatory response elements in astrocytes. Holy grail found: single event in pathogenesis of AD tying together all current hallmarks. |
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| Silver Lake Research Corporation |
Monrovia, CA |
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New immunization system to generate rapid and powerful immune response to a wide range of antigens. Proprietary system: a broadly applicable methodology enabling un-precedented predictability and control over the immune response to even the most "non-immunogenic" antigens. EAP technology platform now being applied to development of monoclonal antibodies for therapeutics, diagnostics, and research uses, where rapid and reliable induction of high-affinity MAbs is crucial. |
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| Southwest Sciences Inc |
Santa Fe, NM |
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With focus in the areas of combustion, atmospheric chemistry, imaging, and optical sci-ences, development of state-of-the-art optical and mass spectrometric technologies |
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| Spectral Sciences Inc |
Burlington, MA |
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SSI is focused to solving clients technical problems from concept to prototype. Involved in areas as diverse as
modeling the complex molecular interactions of rocket engine combustion
and designing a new generation of remote sensing instrumentation for chemical and biological analysis.
SSI scientists bring knowledge built through decades of support programs bearing on new problems in remote sensing, spectroscopy, physical chemistry, combustion, atmos-pheric phenomenology and three dimensional imaging. |
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| Systems and Materials Research Corporation |
Austin, TX |
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Materials and NDE development with specialization and expertise including: * Poly-meric materials development * Elastomers and elastomeric laminates * Guided ultra-sonic wave NDE systems * Tailored sealants and coatings * Underwater connector tech-nology * Material characterization/suitability * Nanocomposites/nanoputties * Micro-wave NDE devices * Reliability Modeling/Analysis * Composite material R&D/applications * Extreme environment materials * NDE requirements/reliability. |
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| Talking Lights LLC |
Boston, MA |
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Context aware computing. A new communication technology using an essential part of every building – lighting – to communicate information that can be heard through an earpiece, seen on a hand-held computer, or processed as data or control signals. Robust, accurate, easy-to-use wireless optoelectronic indoor locators, effortlessly finding people and equipment, tracking their movement, continuously keeping users and central com-puters informed of their whereabouts. Cost effective, efficient, easy to install, accurate and multi-purpose, applications include:
Hospitals, nursing homes and other healthcare facilities
Stores and museums
Building and other security systems
Assistive technologies
Energy monitoring and conservation |
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| Technology Systems Inc |
Brunswick, ME |
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With a current emphasis in Augmented Reality,virtual world system and Planning/Support Systems for Unmanned Vehicles (subsurface, surface, and air) firm offers sophisticated Software Development, Augmented Reality, Simulation, Training Systems and Manufactur-ing Support. Utilizing practical and affordable commercial?off?the?shelf products for the military. TSI also supports non?military ventures through technology integration.
Involved in the simulation industry since 1987. TSI builds on prior successes in video games development and industrial automation. Long established tradition of "firsts" in modeling and simulation including the first group to successfully interface to the SIMNET environment and the first to implement the Distributed Interactive Simulation (DIS) net-work protocol. TSI keeps continuing this tradition of firsts with the development of HLA (High Level Architecture) implementations that exploit the power of this revolutionary dis-tributed objected oriented architecture. |
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| TheraJect Inc |
Fremont, CA |
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An advanced system for transdermal drug delivery envisioned as two major categories of products: TheraJect’s Microeedle Array Transdermal delivery system for drugs: DrugMAT/ and for vaccines: VaxMAT/.
Traditional transdermal drug delivery “patch” systems cannot deliver large molecules such as proteins and vaccines and are incapable of rapid delivery of small molecules such as pain or migraine related drugs.
DrugMAT and VaxMAT can deliver many drugs and vaccines including large molecules such as proteins and gen | | | | |
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